NOG1/YPL093W Summary Help

Standard Name NOG1 1
Systematic Name YPL093W
Feature Type ORF, Verified
Description Putative GTPase; associates with free 60S ribosomal subunits in the nucleolus and is required for 60S ribosomal subunit biogenesis; constituent of 66S pre-ribosomal particles; member of the ODN family of nucleolar G-proteins (1, 2, 3)
Name Description NucleOlar G-protein 1
Chromosomal Location
ChrXVI:370978 to 372921 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All NOG1 GO evidence and references
  View Computational GO annotations for NOG1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 2 genes
Resources
Classical genetics
null
reduction of function
unspecified
Large-scale survey
conditional
null
overexpression
reduction of function
Resources
346 total interaction(s) for 151 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 292
  • Affinity Capture-RNA: 1
  • Affinity Capture-Western: 31
  • Co-fractionation: 2
  • Co-purification: 4
  • Two-hybrid: 4

Genetic Interactions
  • Dosage Rescue: 3
  • Negative Genetic: 6
  • Positive Genetic: 1
  • Synthetic Growth Defect: 2

Resources
Expression Summary
histogram
Resources
Length (a.a.) 647
Molecular Weight (Da) 74,409
Isoelectric Point (pI) 9.38
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXVI:370978 to 372921 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1944 370978..372921 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000006014
References cited on this page View Complete Literature Guide for NOG1
1) Park JH, et al.  (2001) A novel nucleolar G-protein conserved in eukaryotes. J Cell Sci 114(Pt 1):173-185
2) Kallstrom G, et al.  (2003) The putative GTPases Nog1p and Lsg1p are required for 60S ribosomal subunit biogenesis and are localized to the nucleus and cytoplasm, respectively. Mol Cell Biol 23(12):4344-55
3) Horsey EW, et al.  (2004) Role of the yeast Rrp1 protein in the dynamics of pre-ribosome maturation. RNA 10(5):813-27