Standard Name	RLM1 1
Systematic Name	YPL089C
Feature Type	ORF, Verified
Description	MADS-box transcription factor; component of the protein kinase C-mediated MAP kinase pathway involved in the maintenance of cell integrity; phosphorylated and activated by the MAP-kinase Slt2p; RLM1 has a paralog, SMP1, that arose from the whole genome duplication (1, 2, 3, 4, 5, 6)
Name Description	Resistance to Lethality of MKK1P386 overexpression 1

Chromosomal Location	ChrXVI:381150 to 379120 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.

	View Computational GO annotations for RLM1
Molecular Function
Manually curated	DNA binding, bending (IDA) RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity (IDA) sequence-specific DNA binding (IDA)
Biological Process
Manually curated	positive regulation of transcription from RNA polymerase II promoter (IDA) positive regulation of transcription from RNA polymerase II promoter in response to stress (IDA, IMP) signal transduction (IMP)
Cellular Component
Manually curated	nucleus (IDA)

Binding motifs	Predicted RLM1 Binding Site Locations
	CTAWWWWTAG 7 [Search intergenic regions for CTAWWWWTAG]
Resources	ScerTF | YEASTRACT | YeTFaSCo

Classical genetics
null	resistance to Calcofluor White: increased resistance to tunicamycin: decreased resistance to mercaptoethanol: normal resistance to ethylenediaminetetraacetic acid: decreased resistance to caffeine: decreased resistance to sirolimus: decreased resistance to L-1,4-dithiothreitol: decreased toxin resistance: increased
Large-scale survey
null	auxotrophy competitive fitness: decreased resistance to tunicamycin: decreased resistance to hydrogen chloride: decreased resistance to hydroxyurea: increased resistance to camptothecin: increased resistance to bleomycin: increased resistance to 1,4-dithiothreitol: decreased resistance to mycophenolic acid: decreased resistance to L-1,4-dithiothreitol: decreased resistance to glycolaldehyde: decreased resistance to cycloheximide: decreased resistance to trichothecene: increased stress resistance: increased vacuolar morphology: abnormal viable
overexpression	vegetative growth: decreased rate
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	75 total interaction(s) for 52 unique genes/features.
Physical Interactions	Affinity Capture-MS: 7 Affinity Capture-RNA: 1 Affinity Capture-Western: 2 Biochemical Activity: 1 Co-localization: 4 PCA: 2 Protein-RNA: 1 Reconstituted Complex: 1 Two-hybrid: 5
Genetic Interactions	Dosage Rescue: 3 Negative Genetic: 28 Phenotypic Enhancement: 4 Phenotypic Suppression: 2 Positive Genetic: 2 Synthetic Growth Defect: 3 Synthetic Lethality: 7 Synthetic Rescue: 2
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YeastRC | Organelle DB (UMich) | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP | YeastRC
Homologs	Ashbya (AGD) | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrXVI:381150 to 379120 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.
Last Update	Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..2031 381150..379120 2011-02-03 1996-07-31
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain CLIB215 S.c. Strain CLIB324 S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FL100 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain Y10 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain YPS163 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000006010