ARL3/YPL051W Summary

ARL3 BASIC INFORMATION

Standard Name	ARL3 1
Systematic Name	YPL051W
Feature Type	ORF, Verified
Description	GTPase of the Ras superfamily required to recruit Arl1p to the Golgi; similar to ADP-ribosylation factor (1, 2)
Name Description	ADP-Ribosylation factor-Like 1

GO Annotations	All ARL3 GO evidence and references
	View Computational GO annotations for ARL3
Molecular Function
Manually curated	GTPase activity (IDA, ISS)
Biological Process
Manually curated	Golgi to plasma membrane protein transport (IMP) intracellular protein transport (IMP)
Cellular Component
Manually curated	Golgi apparatus (IDA) nuclear envelope-endoplasmic reticulum network (IDA) soluble fraction (IDA)

Mutant Phenotype	All ARL3 Phenotype details and references
Classical genetics
null	resistance to Congo Red: decreased toxin resistance: decreased
Large-scale survey
null	glycogen accumulation: increased competitive fitness: decreased hyperosmotic stress resistance: decreased resistance to rapamycin: decreased resistance to wortmannin: normal resistance to hygromycin B: decreased toxin resistance: decreased viable

Interactions	ARL3 All interactions details and references
	131 total interaction(s) for 65 unique genes/features.
Physical Interactions	Affinity Capture-MS: 4 Affinity Capture-RNA: 2 Affinity Capture-Western: 2
Genetic Interactions	Dosage Rescue: 1 Phenotypic Enhancement: 72 Phenotypic Suppression: 10 Synthetic Growth Defect: 4 Synthetic Lethality: 36

Sequence Information

ChrXVI:459960 to 460556 | |

Last Update

Coordinates: 2004-07-21 | Sequence: 1996-07-31

Subfeature details

	Relative Coordinates	Chromosomal Coordinates	Most Recent Updates
	Relative Coordinates	Chromosomal Coordinates	Coordinates	Sequence
CDS	1..597	459960..460556	2004-07-21	1996-07-31

External Links	All Associated Seq \| Entrez Gene \| Entrez RefSeq Protein \| MIPS \| UniProtKB

Primary SGDID	S000005972

ARL3 RESOURCES

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SGD ORF map	GBrowse

Click on histogram for expression summary
Expression Summary

ADDITIONAL INFORMATION for ARL3

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for ARL3]

1)	Huang CF, et al. (1999) Characterization of a novel ADP-ribosylation factor-like protein (yARL3) in Saccharomyces cerevisiae. J Biol Chem 274(6):3819-27
2)	Behnia R, et al. (2004) Targeting of the Arf-like GTPase Arl3p to the Golgi requires N-terminal acetylation and the membrane protein Sys1p. Nat Cell Biol 6(5):405-13

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