Standard Name	SGF11 1
Systematic Name	YPL047W
Feature Type	ORF, Verified
Description	Integral subunit of SAGA histone acetyltransferase complex, regulates transcription of a subset of SAGA-regulated genes, required for the Ubp8p association with SAGA and for H2B deubiquitylation (1, 2)
Name Description	SaGa associated Factor 11kDa 1

Chromosomal Location	ChrXVI:465962 to 466261 | ORF Map | GBrowse

	View Computational GO annotations for SGF11
Molecular Function
Manually curated	enzyme activator activity (IDA)
Biological Process
Manually curated	histone deubiquitination (IMP) regulation of transcription from RNA polymerase II promoter (IMP)
Cellular Component
Manually curated	DUBm complex (IDA) SAGA complex (IDA)
High-throughput	nucleus (IDA)

Classical genetics
null	viable
Large-scale survey
null	competitive fitness: decreased dessication resistance: decreased resistance to hydroxyurea: decreased resistance to fenpropimorph: decreased resistance to bleomycin: decreased resistance to tunicamycin: increased resistance to sirolimus: increased resistance to mycophenolic acid: increased resistance to fluconazole: increased resistance to methyl methanesulfonate: decreased resistance to sodium selenide: decreased resistance to cycloheximide: increased resistance to benzo[a]pyrene: decreased resistance to trichothecene: increased resistance to (S)-lactic acid: increased resistance to acetic acid: increased resistance to tetramethylammonium: increased resistance to spermine: increased resistance to hygromycin B: increased resistance to hydrogen chloride: increased sporulation efficiency: decreased stress resistance: increased vegetative growth: decreased rate viable
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	424 total interaction(s) for 205 unique genes/features.
Physical Interactions	Affinity Capture-MS: 127 Affinity Capture-RNA: 1 Affinity Capture-Western: 13 Biochemical Activity: 5 Co-crystal Structure: 2 Co-localization: 1 Reconstituted Complex: 3 Two-hybrid: 1
Genetic Interactions	Dosage Growth Defect: 1 Dosage Rescue: 1 Negative Genetic: 152 Phenotypic Suppression: 2 Positive Genetic: 75 Synthetic Growth Defect: 8 Synthetic Lethality: 13 Synthetic Rescue: 19
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YeastRC | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP
Homologs	Ashbya (AGD) | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrXVI:465962 to 466261 | ORF Map | GBrowse
Last Update	Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..300 465962..466261 2011-02-03 1996-07-31
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI1631 S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain CLIB324 S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FL100 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain T73 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000005968