ULP1/YPL020C Summary Help

ULP1 BASIC INFORMATION

Standard Name ULP1
Systematic Name YPL020C
Alias NIB1 1
Feature Type ORF, Verified
Description Ubl (ubiquitin-like protein)-specific protease that cleaves Smt3p protein conjugates; specifically required for cell cycle progression; associates with nucleoporins and may interact with septin rings during telophase (2, 3, 4)
Name Description Ubiquitin-Like Protein
GO Annotations All ULP1 GO evidence and references
    View Computational GO annotations for ULP1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Mutant Phenotype All ULP1 Phenotype details and references
Classical genetics
conditional
reduction of function
Large-scale survey
null
Interactions ULP1 All interactions details and references
86 total interaction(s) for 43 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 15
  • Affinity Capture-RNA: 1
  • Affinity Capture-Western: 8
  • Co-crystal Structure: 1
  • Reconstituted Complex: 4
  • Two-hybrid: 10
Genetic Interactions
  • Dosage Rescue: 10
  • Phenotypic Enhancement: 2
  • Synthetic Growth Defect: 7
  • Synthetic Lethality: 20
  • Synthetic Rescue: 8
Sequence Information
ChrXVI:514176 to 512311 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Last Update Coordinates: 2004-07-21 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates		 Chromosomal
Coordinates		 Most Recent Updates
Coordinates Sequence
CDS 1..1866 514176..512311 2004-07-21 1996-07-31
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | UniProtKB
Primary SGDIDS000005941

ULP1 RESOURCES

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SGD ORF mapGBrowse
SGD ORF map
 GBrowse
  • Literature
  • Retrieve Sequences
  • Sequence Analysis Tools
  • Protein Info & Structure
  • Localization Resources
  • Interactions
  • Phenotype Resources
  • Maps & Displays
  • Comparison Resources
  • Functional Analysis

Click on histogram for expression summary
Expression Summary histogram

ADDITIONAL INFORMATION for ULP1

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for ULP1]

1) Dobson MJ, et al.  (2005) The 2 microm plasmid causes cell death in Saccharomyces cerevisiae with a mutation in Ulp1 protease. Mol Cell Biol 25(10):4299-310
2) Hochstrasser M  (2001) SP-RING for SUMO: new functions bloom for a ubiquitin-like protein. Cell 107(1):5-8
3) Li SJ and Hochstrasser M  (2003) The Ulp1 SUMO isopeptidase: distinct domains required for viability, nuclear envelope localization, and substrate specificity. J Cell Biol 160(7):1069-81
4) Soustelle C, et al.  (2004) A new Saccharomyces cerevisiae strain with a mutant Smt3-deconjugating Ulp1 protein is affected in DNA replication and requires Srs2 and homologous recombination for its viability. Mol Cell Biol 24(12):5130-43