RDR1/YOR380W Summary Help

Standard Name RDR1 1
Systematic Name YOR380W
Feature Type ORF, Verified
Description Transcriptional repressor involved in regulating multidrug resistance; negatively regulates expression of the PDR5 gene; member of the Gal4p family of zinc cluster proteins (1)
Name Description Repressor of Drug Resistance 1
Chromosomal Location
ChrXV:1051290 to 1052930 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All RDR1 GO evidence and references
  View Computational GO annotations for RDR1
Molecular Function
Manually curated
High-throughput
Biological Process
Manually curated
Cellular Component
Manually curated
Targets 10 genes
Regulators 3 genes
Resources
Classical genetics
null
Large-scale survey
null
Resources
21 total interaction(s) for 21 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 1
  • Affinity Capture-RNA: 2
  • Biochemical Activity: 1
  • Two-hybrid: 10

Genetic Interactions
  • Negative Genetic: 6
  • Positive Genetic: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 546
Molecular Weight (Da) 61,287
Isoelectric Point (pI) 7.77
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXV:1051290 to 1052930 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1641 1051290..1052930 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000005907
References cited on this page View Complete Literature Guide for RDR1
1) Hellauer K, et al.  (2002) Zinc cluster protein Rdr1p is a transcriptional repressor of the PDR5 gene encoding a multidrug transporter. J Biol Chem 277(20):17671-6
2) Zhu C, et al.  (2009) High-resolution DNA-binding specificity analysis of yeast transcription factors. Genome Res 19(4):556-66
3) Badis G, et al.  (2008) A library of yeast transcription factor motifs reveals a widespread function for Rsc3 in targeting nucleosome exclusion at promoters. Mol Cell 32(6):878-87