NUD1/YOR373W Summary Help

Standard Name NUD1
Systematic Name YOR373W
Feature Type ORF, Verified
Description Component of the spindle pole body outer plaque; acts through the mitotic exit network to specify asymmetric spindle pole body inheritance (1, 2)
Chromosomal Location
ChrXV:1036834 to 1039389 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All NUD1 GO evidence and references
  View Computational GO annotations for NUD1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Regulators 4 genes
Resources
Classical genetics
conditional
Large-scale survey
null
reduction of function
Resources
58 total interaction(s) for 36 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 12
  • Affinity Capture-RNA: 3
  • Affinity Capture-Western: 9
  • Biochemical Activity: 4
  • Co-localization: 3
  • Co-purification: 1
  • Reconstituted Complex: 1
  • Two-hybrid: 11

Genetic Interactions
  • Dosage Rescue: 6
  • Phenotypic Enhancement: 1
  • Synthetic Growth Defect: 4
  • Synthetic Lethality: 1
  • Synthetic Rescue: 2

Resources
Expression Summary
histogram
Resources
Length (a.a.) 851
Molecular Weight (Da) 94,103
Isoelectric Point (pI) 7.02
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXV:1036834 to 1039389 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..2556 1036834..1039389 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000005900
References cited on this page View Complete Literature Guide for NUD1
1) Adams IR and Kilmartin JV  (1999) Localization of core spindle pole body (SPB) components during SPB duplication in Saccharomyces cerevisiae. J Cell Biol 145(4):809-23
2) Hotz M, et al.  (2012) Spindle pole bodies exploit the mitotic exit network in metaphase to drive their age-dependent segregation. Cell 148(5):958-72