SCP1/YOR367W Summary

SCP1 BASIC INFORMATION

Standard Name	SCP1 1
Systematic Name	YOR367W
Feature Type	ORF, Verified
Description	Component of yeast cortical actin cytoskeleton, binds and cross links actin filaments; originally identified by its homology to calponin (contains a calponin-like repeat) but the Scp1p domain structure is more similar to transgelin (2, 3)
Name Description	S. cerevisiae CalPonin 1

GO Annotations	All SCP1 GO evidence and references
	View Computational GO annotations for SCP1
Molecular Function
Manually curated	actin filament binding (IDA) protein binding, bridging (IDA)
Biological Process
Manually curated	actin filament organization (IDA) chronological cell aging (IGI, IMP)
Cellular Component
Manually curated	actin cortical patch (IDA)

Mutant Phenotype	All SCP1 Phenotype details and references
Large-scale survey
null	viable

Interactions	SCP1 All interactions details and references
	14 total interaction(s) for 3 unique genes/features.
Physical Interactions	Affinity Capture-MS: 1 Affinity Capture-Western: 1 Co-fractionation: 1 Co-localization: 2 Protein-peptide: 2 Reconstituted Complex: 3
Genetic Interactions	Dosage Rescue: 1 Phenotypic Enhancement: 2 Synthetic Growth Defect: 1

Sequence Information

ChrXV:1026005 to 1026607 | |

Last Update

Coordinates: 2006-01-05 | Sequence: 1996-07-31

Subfeature details

	Relative Coordinates	Chromosomal Coordinates	Most Recent Updates
	Relative Coordinates	Chromosomal Coordinates	Coordinates	Sequence
CDS	1..603	1026005..1026607	2006-01-05	1996-07-31

External Links	All Associated Seq \| Entrez Gene \| Entrez RefSeq Protein \| MIPS \| UniProtKB

Primary SGDID	S000005894

SCP1 RESOURCES

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SGD ORF map	GBrowse

Click on histogram for expression summary
Expression Summary

ADDITIONAL INFORMATION for SCP1

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for SCP1]

1)	Epp JA and Chant J (1997) An IQGAP-related protein controls actin-ring formation and cytokinesis in yeast. Curr Biol 7(12):921-9
2)	Goodman A, et al. (2003) The Saccharomyces cerevisiae calponin/transgelin homolog Scp1 functions with fimbrin to regulate stability and organization of the actin cytoskeleton. Mol Biol Cell 14(7):2617-29
3)	Winder SJ, et al. (2003) SCP1 encodes an actin-bundling protein in yeast. Biochem J 375(Pt 2):287-95

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