SCP1/YOR367W Summary Help

Standard Name SCP1 1
Systematic Name YOR367W
Feature Type ORF, Verified
Description Component of yeast cortical actin cytoskeleton; binds and cross links actin filaments; originally identified by its homology to calponin (contains a calponin-like repeat) but the Scp1p domain structure is more similar to transgelin (2, 3)
Name Description S. cerevisiae CalPonin 1
Chromosomal Location
ChrXV:1026007 to 1026609 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All SCP1 GO evidence and references
  View Computational GO annotations for SCP1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Regulators 8 genes
Resources
Classical genetics
null
overexpression
Large-scale survey
null
unspecified
Resources
25 total interaction(s) for 13 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 2
  • Affinity Capture-RNA: 4
  • Affinity Capture-Western: 1
  • Co-fractionation: 1
  • Co-localization: 2
  • Protein-peptide: 2
  • Reconstituted Complex: 3

Genetic Interactions
  • Dosage Rescue: 1
  • Negative Genetic: 2
  • Phenotypic Enhancement: 4
  • Phenotypic Suppression: 1
  • Synthetic Growth Defect: 1
  • Synthetic Rescue: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 200
Molecular Weight (Da) 22,748
Isoelectric Point (pI) 9.47
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXV:1026007 to 1026609 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..603 1026007..1026609 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000005894
References cited on this page View Complete Literature Guide for SCP1
1) Epp JA and Chant J  (1997) An IQGAP-related protein controls actin-ring formation and cytokinesis in yeast. Curr Biol 7(12):921-9
2) Goodman A, et al.  (2003) The Saccharomyces cerevisiae calponin/transgelin homolog Scp1 functions with fimbrin to regulate stability and organization of the actin cytoskeleton. Mol Biol Cell 14(7):2617-29
3) Winder SJ, et al.  (2003) SCP1 encodes an actin-bundling protein in yeast. Biochem J 375(Pt 2):287-95