TYE7/YOR344C Summary Help

TYE7 BASIC INFORMATION

Standard Name TYE7
Systematic Name YOR344C
Alias SGC1
Feature Type ORF, Verified
Description Serine-rich protein that contains a basic-helix-loop-helix (bHLH) DNA binding motif; binds E-boxes of glycolytic genes and contributes to their activation; may function as a transcriptional activator in Ty1-mediated gene expression (1, 2, 3)
Name Description Ty-mediated Expression
GO Annotations All TYE7 GO evidence and references
    View Computational GO annotations for TYE7
Molecular Function
Manually curated
High-throughput
Biological Process
Manually curated
Cellular Component
Manually curated
Regulatory Role
Binding motifs TYE7 Transcription Factor Binding Sites and References
  • TCACGTGA
  • TCTGGCACACA
Mutant Phenotype All TYE7 Phenotype details and references
Large-scale survey
null
Interactions TYE7 All interactions details and references
10 total interaction(s) for 9 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 1
  • Affinity Capture-RNA: 1
  • Affinity Capture-Western: 1
  • Biochemical Activity: 3
  • Reconstituted Complex: 1
  • Two-hybrid: 1
Genetic Interactions
  • Dosage Rescue: 1
  • Synthetic Growth Defect: 1
Sequence Information
ChrXV:978066 to 977191 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Genetic position: 199 cM
Last Update Coordinates: 2006-01-05 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates		 Chromosomal
Coordinates		 Most Recent Updates
Coordinates Sequence
CDS 1..876 978066..977191 2006-01-05 1996-07-31
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | UniProtKB
Primary SGDIDS000005871

TYE7 RESOURCES

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SGD ORF mapGBrowse
SGD ORF map
 GBrowse
  • Literature
  • Retrieve Sequences
  • Sequence Analysis Tools
  • Protein Info & Structure
  • Localization Resources
  • Interactions
  • Phenotype Resources
  • Maps & Displays
  • Comparison Resources
  • Functional Analysis

Click on histogram for expression summary
Expression Summary histogram

ADDITIONAL INFORMATION for TYE7

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for TYE7]

1) Nishi K, et al.  (1995) The GCR1 requirement for yeast glycolytic gene expression is suppressed by dominant mutations in the SGC1 gene, which encodes a novel basic-helix-loop-helix protein. Mol Cell Biol 15(5):2646-53
2) Sato T, et al.  (1999) The E-box DNA binding protein Sgc1p suppresses the gcr2 mutation, which is involved in transcriptional activation of glycolytic genes in Saccharomyces cerevisiae. FEBS Lett 463(3):307-11
3) Lohning C and Ciriacy M  (1994) The TYE7 gene of Saccharomyces cerevisiae encodes a putative bHLH-LZ transcription factor required for Ty1-mediated gene expression. Yeast 10(10):1329-39