Standard Name	MRS2 1
Systematic Name	YOR334W
Feature Type	ORF, Verified
Description	Mitochondrial inner membrane Mg(2+) channel, required for maintenance of intramitochondrial Mg(2+) concentrations at the correct level to support splicing of group II introns (2, 3)
Name Description	Mitochondrial RNA Splicing 4

Chromosomal Location	ChrXV:944596 to 946008 | ORF Map | GBrowse

	View Computational GO annotations for MRS2
Molecular Function
Manually curated	magnesium ion transmembrane transporter activity (IDA, IGI, IMP, ISS)
Biological Process
Manually curated	mitochondrial magnesium ion transport (IDA, IGI, IMP, ISS)
Cellular Component
Manually curated	mitochondrial inner membrane (IDA)
High-throughput	integral to membrane (ISM) mitochondrion (IDA)

Classical genetics
null	unspliced group II introns in mitochondrial transcripts accumulation: increased magnesium(2+) accumulation: decreased respiratory metabolism: decreased
Large-scale survey
null	polyphosphate accumulation: abnormal competitive fitness: normal dessication resistance: decreased haploinsufficient resistance to hygromycin B: decreased resistance to elesclomol-Cu: decreased resistance to spermine: decreased respiratory growth: decreased rate starvation resistance: decreased utilization of carbon source: decreased vacuolar morphology: abnormal viable
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	70 total interaction(s) for 58 unique genes/features.
Physical Interactions	Affinity Capture-MS: 2 Affinity Capture-Western: 1 Biochemical Activity: 1 Two-hybrid: 7
Genetic Interactions	Dosage Growth Defect: 1 Dosage Rescue: 10 Negative Genetic: 47 Positive Genetic: 1
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YeastRC | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP
Homologs	Ashbya (AGD) | CGD Homologs | CandidaDB Homologs | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrXV:944596 to 946008 | ORF Map | GBrowse
Last Update	Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..1413 944596..946008 2011-02-03 1996-07-31
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain T73 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | TCDB | UniProtKB

Primary SGDID	S000005861