HSH49/YOR319W Summary Help

HSH49 BASIC INFORMATION

Standard Name HSH49
Systematic Name YOR319W
Feature Type ORF, Verified
Description U2-snRNP associated splicing factor with similarity to the mammalian splicing factor SAP49; proposed to function as a U2-snRNP assembly factor along with Hsh155p and binding partner Cus1p; contains two RNA recognition motifs (RRM) (1, 2, 3, 4)
Name Description Human Sap Homolog 3
GO Annotations All HSH49 GO evidence and references
    View Computational GO annotations for HSH49
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Mutant Phenotype All HSH49 Phenotype details and references
Classical genetics
null
Large-scale survey
null
Interactions HSH49 All interactions details and references
46 total interaction(s) for 26 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 26
  • Affinity Capture-RNA: 1
  • Affinity Capture-Western: 1
  • Co-purification: 1
  • Reconstituted Complex: 1
  • Two-hybrid: 15
Genetic Interactions
  • Synthetic Growth Defect: 1
Sequence Information
ChrXV:912819 to 913460 | ORF Map | GBrowse
Gbrowse
Last Update Coordinates: 2006-01-05 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates		 Chromosomal
Coordinates		 Most Recent Updates
Coordinates Sequence
CDS 1..642 912819..913460 2006-01-05 1996-07-31
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | UniProtKB
Primary SGDIDS000005846

HSH49 RESOURCES

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SGD ORF mapGBrowse
SGD ORF map
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  • Literature
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  • Protein Info & Structure
  • Localization Resources
  • Interactions
  • Phenotype Resources
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  • Functional Analysis

Click on histogram for expression summary
Expression Summary histogram

ADDITIONAL INFORMATION for HSH49

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for HSH49]

1) Pauling MH, et al.  (2000) Functional Cus1p is found with Hsh155p in a multiprotein splicing factor associated with U2 snRNA. Mol Cell Biol 20(6):2176-85
2) Igel H, et al.  (1998) Conservation of structure and subunit interactions in yeast homologues of splicing factor 3b (SF3b) subunits. RNA 4(1):1-10
3) Wells SE, et al.  (1996) CUS1, a suppressor of cold-sensitive U2 snRNA mutations, is a novel yeast splicing factor homologous to human SAP 145. Genes Dev 10(2):220-32
4) Stevens SW, et al.  (2002) Composition and functional characterization of the yeast spliceosomal penta-snRNP. Mol Cell 9(1):31-44