SNU66/YOR308C Summary Help

SNU66 BASIC INFORMATION

Standard Name SNU66
Systematic Name YOR308C
Feature Type ORF, Verified
Description Component of the U4/U6.U5 snRNP complex involved in pre-mRNA splicing via spliceosome; has homology to human SART-1 and to an S. pombe protein; snu66 null mutation confers cold-sensitivity but is not lethal at normal growth temperatures (1, 2)
Name Description Small NUclear ribonucleoprotein associated 1
GO Annotations All SNU66 GO evidence and references
    View Computational GO annotations for SNU66
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Mutant Phenotype All SNU66 Phenotype details and references
Classical genetics
null
Large-scale survey
null
Interactions SNU66 All interactions details and references
185 total interaction(s) for 118 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 63
  • Affinity Capture-Western: 2
  • Co-purification: 3
  • Protein-RNA: 1
  • Two-hybrid: 9

Genetic Interactions
  • Dosage Growth Defect: 1
  • Phenotypic Enhancement: 77
  • Phenotypic Suppression: 15
  • Synthetic Growth Defect: 8
  • Synthetic Lethality: 6

Sequence Information
ChrXV:896384 to 894621 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Last Update Coordinates: 2006-01-05 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1764 896384..894621 2006-01-05 1996-07-31
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | UniProtKB
Primary SGDIDS000005835

SNU66 RESOURCES

Click on map for expanded view
SGD ORF mapGBrowse
SGD ORF map
GBrowse
  • Literature
  • Retrieve Sequences
  • Sequence Analysis Tools
  • Protein Info & Structure
  • Localization Resources
  • Interactions
  • Phenotype Resources
  • Maps & Displays
  • Comparison Resources
  • Functional Analysis

Click on histogram for expression summary
Expression Summary histogram

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for SNU66]

1) Stevens SW and Abelson J  (1999) Purification of the yeast U4/U6.U5 small nuclear ribonucleoprotein particle and identification of its proteins. Proc Natl Acad Sci U S A 96(13):7226-31
2) Stevens SW, et al.  (2001) Biochemical and genetic analyses of the U5, U6, and U4/U6 x U5 small nuclear ribonucleoproteins from Saccharomyces cerevisiae. RNA 7(11):1543-53