MCH5/YOR306C Summary Help

Standard Name MCH5 1
Systematic Name YOR306C
Feature Type ORF, Verified
Description Plasma membrane riboflavin transporter; facilitates the uptake of vitamin B2; required for FAD-dependent processes; sequence similarity to mammalian monocarboxylate permeases, however mutants are not deficient in monocarboxylate transport (1, 2)
Name Description MonoCarboxylate transporter Homologue 1
Chromosomal Location
ChrXV:891432 to 889867 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All MCH5 GO evidence and references
  View Computational GO annotations for MCH5
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 13 genes
Resources
Classical genetics
null
Large-scale survey
null
overexpression
Resources
9 total interaction(s) for 7 unique genes/features.
Physical Interactions
  • PCA: 1
  • Reconstituted Complex: 1

Genetic Interactions
  • Negative Genetic: 4
  • Synthetic Growth Defect: 2
  • Synthetic Rescue: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 521
Molecular Weight (Da) 57,582
Isoelectric Point (pI) 5.41
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXV:891432 to 889867 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 2011-02-03
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1566 891432..889867 2011-02-03 2011-02-03
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000005833
References cited on this page View Complete Literature Guide for MCH5
1) Reihl P and Stolz J  (2005) The monocarboxylate transporter homolog Mch5p catalyzes riboflavin (vitamin B2) uptake in Saccharomyces cerevisiae. J Biol Chem 280(48):39809-17
2) Makuc J, et al.  (2001) The putative monocarboxylate permeases of the yeast Saccharomyces cerevisiae do not transport monocarboxylic acids across the plasma membrane. Yeast 18(12):1131-43