NOC2/YOR206W Summary

NOC2 BASIC INFORMATION

Standard Name	NOC2 1
Systematic Name	YOR206W
Feature Type	ORF, Verified
Description	Protein that forms a nucleolar complex with Mak21p that binds to 90S and 66S pre-ribosomes, as well as a nuclear complex with Noc3p that binds to 66S pre-ribosomes; both complexes mediate intranuclear transport of ribosomal precursors (1)
Name Description	NucleOlar Complex associated 1

GO Annotations	All NOC2 GO evidence and references
	View Computational GO annotations for NOC2
Molecular Function
Manually curated	molecular_function unknown (ND)
Biological Process
Manually curated	ribosomal subunit export from nucleus (TAS) ribosome assembly (TAS)
Cellular Component
Manually curated	Noc1p-Noc2p complex (IPI) Noc2p-Noc3p complex (IPI) nucleus (IDA)
High-throughput	mitochondrion (IDA)

Mutant Phenotype	All NOC2 Phenotype details and references
Large-scale survey
conditional	heat sensitivity: increased
null	competitive fitness: decreased haploinsufficient inviable

Interactions	NOC2 All interactions details and references
	168 total interaction(s) for 82 unique genes/features.
Physical Interactions	Affinity Capture-MS: 141 Affinity Capture-Western: 8 Co-purification: 1 PCA: 10 Two-hybrid: 1
Genetic Interactions	Synthetic Growth Defect: 1 Synthetic Lethality: 6

Sequence Information

ChrXV:727513 to 729645 | |

Last Update

Coordinates: 2006-01-05 | Sequence: 1996-07-31

Subfeature details

	Relative Coordinates	Chromosomal Coordinates	Most Recent Updates
	Relative Coordinates	Chromosomal Coordinates	Coordinates	Sequence
CDS	1..2133	727513..729645	2006-01-05	1996-07-31

External Links	All Associated Seq \| Entrez Gene \| Entrez RefSeq Protein \| MIPS \| UniProtKB

Primary SGDID	S000005732

NOC2 RESOURCES

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SGD ORF map	GBrowse

Click on histogram for expression summary
Expression Summary

ADDITIONAL INFORMATION for NOC2

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for NOC2]

1)	Milkereit P, et al. (2001) Maturation and intranuclear transport of pre-ribosomes requires Noc proteins. Cell 105(4):499-509

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