LIP5/YOR196C Summary Help

Standard Name LIP5 1
Systematic Name YOR196C
Feature Type ORF, Verified
Description Protein involved in biosynthesis of the coenzyme lipoic acid; has similarity to E. coli lipoic acid synthase (1, 2)
Name Description LIPoic acid 1
Chromosomal Location
ChrXV:716837 to 715593 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All LIP5 GO evidence and references
  View Computational GO annotations for LIP5
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
High-throughput
Regulators 86 genes
Resources
Classical genetics
null
Large-scale survey
null
unspecified
Resources
144 total interaction(s) for 140 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 10
  • Affinity Capture-RNA: 1
  • Biochemical Activity: 3

Genetic Interactions
  • Negative Genetic: 112
  • Positive Genetic: 11
  • Synthetic Growth Defect: 5
  • Synthetic Lethality: 1
  • Synthetic Rescue: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 414
Molecular Weight (Da) 46,247
Isoelectric Point (pI) 10.26
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXV:716837 to 715593 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1245 716837..715593 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000005722
References cited on this page View Complete Literature Guide for LIP5
1) Sulo P and Martin NC  (1993) Isolation and characterization of LIP5. A lipoate biosynthetic locus of Saccharomyces cerevisiae. J Biol Chem 268(23):17634-9
2) Schonauer MS, et al.  (2009) Lipoic Acid synthesis and attachment in yeast mitochondria. J Biol Chem 284(35):23234-42