NFI1/YOR156C Summary Help

NFI1 BASIC INFORMATION

Standard Name NFI1 1
Systematic Name YOR156C
Alias SIZ2 2
Feature Type ORF, Verified
Description SUMO ligase, catalyzes the covalent attachment of SUMO (Smt3p) to proteins; involved in maintenance of proper telomere length (3, 4, 5)
GO Annotations All NFI1 GO evidence and references
    View Computational GO annotations for NFI1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Mutant Phenotype All NFI1 Phenotype details and references
Classical genetics
null
Large-scale survey
null
Interactions NFI1 All interactions details and references
74 total interaction(s) for 48 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 6
  • Affinity Capture-Western: 1
  • Biochemical Activity: 3
  • Reconstituted Complex: 1
  • Two-hybrid: 23
Genetic Interactions
  • Dosage Rescue: 1
  • Phenotypic Enhancement: 5
  • Phenotypic Suppression: 6
  • Synthetic Growth Defect: 22
  • Synthetic Lethality: 5
  • Synthetic Rescue: 1
Sequence Information
ChrXV:630541 to 628361 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Last Update Coordinates: 2006-01-05 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates		 Chromosomal
Coordinates		 Most Recent Updates
Coordinates Sequence
CDS 1..2181 630541..628361 2006-01-05 1996-07-31
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | UniProtKB
Primary SGDIDS000005682

NFI1 RESOURCES

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SGD ORF mapGBrowse
SGD ORF map
 GBrowse
  • Literature
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  • Sequence Analysis Tools
  • Protein Info & Structure
  • Localization Resources
  • Interactions
  • Phenotype Resources
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  • Functional Analysis

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Expression Summary histogram

ADDITIONAL INFORMATION for NFI1

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for NFI1]

1) de Virgilio, C. and J.R. Pringle  (1995) S. cerevisiae two-hybrid interactor with the C-terminus of Cdc12p. Unpublished
2) Strunnikov AV, et al.  (2001) Saccharomyces cerevisiae SMT4 encodes an evolutionarily conserved protease with a role in chromosome condensation regulation. Genetics 158(1):95-107
3) Johnson ES and Gupta AA  (2001) An E3-like factor that promotes SUMO conjugation to the yeast septins. Cell 106(6):735-44
4) Hochstrasser M  (2001) SP-RING for SUMO: new functions bloom for a ubiquitin-like protein. Cell 107(1):5-8
5) Askree SH, et al.  (2004) A genome-wide screen for Saccharomyces cerevisiae deletion mutants that affect telomere length. Proc Natl Acad Sci U S A 101(23):8658-63