LSC1/YOR142W Summary Help

Standard Name LSC1 1
Systematic Name YOR142W
Feature Type ORF, Verified
Description Alpha subunit of succinyl-CoA ligase; succinyl-CoA ligase is a mitochondrial enzyme of the TCA cycle that catalyzes the nucleotide-dependent conversion of succinyl-CoA to succinate; phosphorylated (1, 2)
Name Description Ligase of Succinyl-CoA 1
Chromosomal Location
ChrXV:593057 to 594046 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All LSC1 GO evidence and references
  View Computational GO annotations for LSC1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 87 genes
Resources
Pathways
Classical genetics
null
Large-scale survey
null
unspecified
Resources
66 total interaction(s) for 55 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 14
  • Affinity Capture-RNA: 4

Genetic Interactions
  • Dosage Lethality: 1
  • Negative Genetic: 41
  • Phenotypic Suppression: 1
  • Positive Genetic: 5

Resources
Expression Summary
histogram
Resources
Length (a.a.) 329
Molecular Weight (Da) 35,032
Isoelectric Point (pI) 8.73
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXV:593057 to 594046 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..990 593057..594046 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000005668
References cited on this page View Complete Literature Guide for LSC1
1) Przybyla-Zawislak B, et al.  (1998) Genes of succinyl-CoA ligase from Saccharomyces cerevisiae. Eur J Biochem 258(2):736-43
2) Reinders J, et al.  (2007) Profiling phosphoproteins of yeast mitochondria reveals a role of phosphorylation in assembly of the ATP synthase. Mol Cell Proteomics 6(11):1896-906