CAT5/YOR125C Summary Help

Standard Name CAT5
Systematic Name YOR125C
Alias COQ7
Feature Type ORF, Verified
Description Protein required for ubiquinone (Coenzyme Q) biosynthesis; localizes to the matrix face of the mitochondrial inner membrane in a large complex with ubiquinone biosynthetic enzymes; required for gluconeogenic gene activation (1, 2, 3, 4)
Name Description CATabolite repression
Chromosomal Location
ChrXV:559731 to 559030 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All CAT5 GO evidence and references
  View Computational GO annotations for CAT5
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 3 genes
Resources
Pathways
Classical genetics
gain of function
null
Large-scale survey
null
Resources
120 total interaction(s) for 116 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 5
  • Affinity Capture-RNA: 3
  • Affinity Capture-Western: 1
  • Biochemical Activity: 1
  • Co-fractionation: 2
  • PCA: 1

Genetic Interactions
  • Dosage Rescue: 1
  • Negative Genetic: 94
  • Phenotypic Enhancement: 2
  • Phenotypic Suppression: 1
  • Positive Genetic: 4
  • Synthetic Growth Defect: 5

Resources
Expression Summary
histogram
Resources
Length (a.a.) 233
Molecular Weight (Da) 26,059
Isoelectric Point (pI) 8.04
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXV:559731 to 559030 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 2003-09-22
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..702 559731..559030 2011-02-03 2003-09-22
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000005651
References cited on this page View Complete Literature Guide for CAT5
1) Jonassen T, et al.  (1998) Yeast Clk-1 homologue (Coq7/Cat5) is a mitochondrial protein in coenzyme Q synthesis. J Biol Chem 273(6):3351-7
2) Jonassen T, et al.  (1996) Isolation and sequencing of the rat Coq7 gene and the mapping of mouse Coq7 to chromosome 7. Arch Biochem Biophys 330(2):285-9
3) Marbois BN and Clarke CF  (1996) The COQ7 gene encodes a protein in saccharomyces cerevisiae necessary for ubiquinone biosynthesis. J Biol Chem 271(6):2995-3004
4) Hsieh EJ, et al.  (2007) Saccharomyces cerevisiae Coq9 polypeptide is a subunit of the mitochondrial coenzyme Q biosynthetic complex. Arch Biochem Biophys 463(1):19-26