RPT5/YOR117W Summary Help

RPT5 BASIC INFORMATION

Standard Name RPT5 1
Systematic Name YOR117W
Alias YTA1 2
Feature Type ORF, Verified
Description One of six ATPases of the 19S regulatory particle of the 26S proteasome involved in the degradation of ubiquitinated substrates; recruited to the GAL1-10 promoter region upon induction of transcription (3, 4, 5, 6)
Name Description Regulatory Particle Triple-A protein, or Regulatory Particle Triphosphatase 1
GO Annotations All RPT5 GO evidence and references
    View Computational GO annotations for RPT5
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Mutant Phenotype All RPT5 Phenotype details and references
Large-scale survey
null
Interactions RPT5 All interactions details and references
405 total interaction(s) for 281 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 298
  • Affinity Capture-Western: 29
  • Biochemical Activity: 2
  • Co-fractionation: 3
  • Co-purification: 7
  • PCA: 6
  • Reconstituted Complex: 2
  • Two-hybrid: 18
Genetic Interactions
  • Synthetic Growth Defect: 3
  • Synthetic Rescue: 37
Sequence Information
ChrXV:545030 to 546334 | ORF Map | GBrowse
Gbrowse
Last Update Coordinates: 2006-01-05 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates		 Chromosomal
Coordinates		 Most Recent Updates
Coordinates Sequence
CDS 1..1305 545030..546334 2006-01-05 1996-07-31
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | UniProtKB
Primary SGDIDS000005643

RPT5 RESOURCES

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SGD ORF mapGBrowse
SGD ORF map
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  • Protein Info & Structure
  • Localization Resources
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  • Functional Analysis

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Expression Summary histogram

ADDITIONAL INFORMATION for RPT5

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for RPT5]

1) Finley D, et al.  (1998) Unified nomenclature for subunits of the Saccharomyces cerevisiae proteasome regulatory particle. Trends Biochem Sci 23(7):244-5
2) Schnall R, et al.  (1994) Identification of a set of yeast genes coding for a novel family of putative ATPases with high similarity to constituents of the 26S protease complex. Yeast 10(9):1141-55
3) Glickman MH, et al.  (1998) The regulatory particle of the Saccharomyces cerevisiae proteasome. Mol Cell Biol 18(6):3149-62
4) Glickman MH, et al.  (1999) Functional analysis of the proteasome regulatory particle. Mol Biol Rep 26(1-2):21-8
5) Rubin DM, et al.  (1998) Active site mutants in the six regulatory particle ATPases reveal multiple roles for ATP in the proteasome. EMBO J 17(17):4909-19
6) Gonzalez F, et al.  (2002) Recruitment of a 19S proteasome subcomplex to an activated promoter. Science 296(5567):548-50