Standard Name	TFC7 1 (see Nomenclature conflict Note)
Systematic Name	YOR110W
Feature Type	ORF, Verified
Description	RNA pol III transcription initiation factor complex (TFIIIC) subunit; part of the TauA globular domain of TFIIIC that binds DNA at the BoxA promoter sites of tRNA and similar genes; TFC7 has a paralog, YNL108C, that arose from the whole genome duplication (2, 3, 4)
Gene Product Alias	tau 55 1

Chromosomal Location	ChrXV:528941 to 530248 | ORF Map | GBrowse

	View Computational GO annotations for TFC7
Molecular Function
Manually curated	contributes_to DNA binding, bending (IDA) contributes_to RNA polymerase III type 1 promoter sequence-specific DNA binding (IDA) contributes_to RNA polymerase III type 1 promoter sequence-specific DNA binding TFIIIB recruiting transcription factor activity (IDA) contributes_to RNA polymerase III type 2 promoter sequence-specific DNA binding (IDA) contributes_to RNA polymerase III type 2 promoter sequence-specific DNA binding TFIIIB recruiting transcription factor activity (IDA) contributes_to sequence-specific DNA binding RNA polymerase III transcription factor activity (IDA, IMP)
Biological Process
Manually curated	5S class rRNA transcription from RNA polymerase III type 1 promoter (IDA) transcription from a RNA polymerase III hybrid type promoter (IDA) transcription from RNA polymerase III type 2 promoter (IDA, IMP)
Cellular Component
Manually curated	transcription factor TFIIIC complex (IDA)

Classical genetics
null	trehalose accumulation: decreased inviable
Large-scale survey
null	haploinsufficient
reduction of function	competitive fitness: increased
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	48 total interaction(s) for 22 unique genes/features.
Physical Interactions	Affinity Capture-MS: 23 Affinity Capture-RNA: 2 Affinity Capture-Western: 8 Biochemical Activity: 2 Co-fractionation: 1 PCA: 5 Reconstituted Complex: 1 Two-hybrid: 4
Genetic Interactions	Dosage Rescue: 2
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YeastRC | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP | YeastRC
Homologs	Ashbya (AGD) | AspGD Homologs | CGD Homologs | CandidaDB Homologs | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrXV:528941 to 530248 | ORF Map | GBrowse
Last Update	Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..1308 528941..530248 2011-02-03 1996-07-31
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI1631 S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain EC1118 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain YJM789 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000005636