ATX2/YOR079C Summary Help

Standard Name ATX2 1
Systematic Name YOR079C
Alias YOR29-30
Feature Type ORF, Verified
Description Golgi membrane protein involved in manganese homeostasis; overproduction suppresses the sod1 (copper, zinc superoxide dismutase) null mutation (2)
Name Description AnTioXidant 1
Chromosomal Location
ChrXV:474416 to 473475 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All ATX2 GO evidence and references
  View Computational GO annotations for ATX2
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 3 genes
Resources
Large-scale survey
null
overexpression
Resources
23 total interaction(s) for 16 unique genes/features.
Physical Interactions
  • PCA: 3

Genetic Interactions
  • Dosage Rescue: 2
  • Negative Genetic: 12
  • Positive Genetic: 6

Resources
Expression Summary
histogram
Resources
Length (a.a.) 313
Molecular Weight (Da) 34,408
Isoelectric Point (pI) 5.07
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXV:474416 to 473475 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..942 474416..473475 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000005605
References cited on this page View Complete Literature Guide for ATX2
1) Lin SJ and Culotta VC  (1995) The ATX1 gene of Saccharomyces cerevisiae encodes a small metal homeostasis factor that protects cells against reactive oxygen toxicity. Proc Natl Acad Sci U S A 92(9):3784-8
2) Lin SJ and Culotta VC  (1996) Suppression of oxidative damage by Saccharomyces cerevisiae ATX2, which encodes a manganese-trafficking protein that localizes to Golgi-like vesicles. Mol Cell Biol 16(11):6303-12