GYP1/YOR070C Summary Help

GYP1 BASIC INFORMATION

Standard Name GYP1
Systematic Name YOR070C
Alias YOR29-21
Feature Type ORF, Verified
Description Cis-golgi GTPase-activating protein (GAP) for the Rab family members Ypt1p (in vivo) and for Ypt1p, Sec4p, Ypt7p, and Ypt51p (in vitro); involved in vesicle docking and fusion (1, 2, 3, 4, 5)
Name Description Gtpase-activating protein for YPt1p 1
GO Annotations All GYP1 GO evidence and references
    View Computational GO annotations for GYP1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Mutant Phenotype All GYP1 Phenotype details and references
Classical genetics
null
Large-scale survey
null
Interactions GYP1 All interactions details and references
213 total interaction(s) for 104 unique genes/features.
Physical Interactions
  • Affinity Capture-RNA: 1
  • Biochemical Activity: 7
  • Reconstituted Complex: 1
  • Two-hybrid: 2
Genetic Interactions
  • Dosage Lethality: 2
  • Dosage Rescue: 1
  • Phenotypic Enhancement: 102
  • Phenotypic Suppression: 10
  • Synthetic Growth Defect: 23
  • Synthetic Lethality: 62
  • Synthetic Rescue: 2
Sequence Information
ChrXV:457822 to 455909 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Last Update Coordinates: 2006-01-05 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates		 Chromosomal
Coordinates		 Most Recent Updates
Coordinates Sequence
CDS 1..1914 457822..455909 2006-01-05 1996-07-31
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | UniProtKB
Primary SGDIDS000005596

GYP1 RESOURCES

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SGD ORF mapGBrowse
SGD ORF map
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  • Localization Resources
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  • Functional Analysis

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Expression Summary histogram

ADDITIONAL INFORMATION for GYP1

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for GYP1]

1) Du LL, et al.  (1998) Identification of a Sec4p GTPase-activating protein (GAP) as a novel member of a Rab GAP family. J Biol Chem 273(6):3253-6
2) Albert S, et al.  (1999) Identification of the catalytic domains and their functionally critical arginine residues of two yeast GTPase-activating proteins specific for Ypt/Rab transport GTPases. EMBO J 18(19):5216-25
3) Jones S, et al.  (1998) Identification of regulators for Ypt1 GTPase nucleotide cycling. Mol Biol Cell 9(10):2819-37
4) Du LL and Novick P  (2001) Yeast rab GTPase-activating protein Gyp1p localizes to the Golgi apparatus and is a negative regulator of Ypt1p. Mol Biol Cell 12(5):1215-26
5) Wang L, et al.  (2003) Hierarchy of protein assembly at the vertex ring domain for yeast vacuole docking and fusion. J Cell Biol 160(3):365-74