| Standard Name | YNG1 |
|---|---|
| Systematic Name | YOR064C |
| Alias | YOR29-15 |
| Feature Type | ORF, Verified |
| Description | Subunit of the NuA3 histone acetyltransferase complex that acetylates histone H3; contains PHD finger domain that interacts with methylated histone H3, has similarity to the human tumor suppressor ING1 (1, 2, 3, 4) |
| Name Description | Yeast homolog of mammalian Ing1 |
| Chromosomal Location | |
|---|---|
| Note: this feature is encoded on the Crick strand. | |
Gene Ontology Annotations All YNG1 GO evidence and references
| View Computational GO annotations for YNG1 | |
| Molecular Function | |
| Manually curated | |
| Biological Process | |
| Manually curated | |
| Cellular Component | |
| Manually curated |
Mutant phenotypes All YNG1 Phenotype evidence and references
| Classical genetics | |
|---|---|
| null | |
| overexpression | |
| Large-scale survey | |
| null |
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| overexpression | |
| Resources |
interactions All YNG1 Interaction evidence and references
| 77 total interaction(s) for 53 unique genes/features. | |
| Physical Interactions |
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| Genetic Interactions |
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| Resources |
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Expression Summary
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| Resources |
Protein Information All YNG1 Protein evidence and references
| Localization | |
|---|---|
| Phosphorylation | PhosphoGRID | PhosphoPep Database |
| Structure | |
| Homologs |
sequence information
| Note: this feature is encoded on the Crick strand. | |||||||||||||
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| Last Update | Coordinates: 2011-02-03 | Sequence: 1996-07-31 | ||||||||||||
| Subfeature details |
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Analyze Sequence
| S288C only | |
|---|---|
| S288C vs. other species | |
| S288C vs. other strains |
Resources
| External Links | All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB |
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| Primary SGDID | S000005590 |
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References cited on this page View Complete Literature Guide for YNG1
| 1) | Loewith R, et al. (2000) Three yeast proteins related to the human candidate tumor suppressor p33(ING1) are associated with histone acetyltransferase activities. Mol Cell Biol 20(11):3807-16 |
| 2) | Howe L, et al. (2002) Yng1p modulates the activity of Sas3p as a component of the yeast NuA3 Hhistone acetyltransferase complex. Mol Cell Biol 22(14):5047-53 |
| 3) | Martin DG, et al. (2006) The Yng1p plant homeodomain finger is a methyl-histone binding module that recognizes lysine 4-methylated histone H3. Mol Cell Biol 26(21):7871-9 |
| 4) | Taverna SD, et al. (2006) Yng1 PHD finger binding to H3 trimethylated at K4 promotes NuA3 HAT activity at K14 of H3 and transcription at a subset of targeted ORFs. Mol Cell 24(5):785-96 |




