YOR059C Summary Help

Systematic Name YOR059C
Alias YOR29-10
Feature Type ORF, Verified
Description Lipid particle protein of unknown function; contains a putative lipase serine active site; induced by transcription factor Rpn4p; protein abundance increases in response to DNA replication stress (1, 2, 3, 4)
Chromosomal Location
ChrXV:440258 to 438906 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All YOR059C GO evidence and references
  View Computational GO annotations for YOR059C
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Regulators 78 genes
Resources
Large-scale survey
null
Resources
20 total interaction(s) for 18 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 4
  • Affinity Capture-RNA: 2
  • Co-fractionation: 1
  • Two-hybrid: 2

Genetic Interactions
  • Negative Genetic: 8
  • Positive Genetic: 2
  • Synthetic Lethality: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 450
Molecular Weight (Da) 51,105
Isoelectric Point (pI) 9.81
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXV:440258 to 438906 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1353 440258..438906 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000005585
References cited on this page View Complete Literature Guide for YOR059C
1) Athenstaedt K, et al.  (1999) Identification and characterization of major lipid particle proteins of the yeast Saccharomyces cerevisiae. J Bacteriol 181(20):6441-8
2) Wagner A, et al.  (2009) Mobilization of steryl esters from lipid particles of the yeast Saccharomyces cerevisiae. Biochim Biophys Acta 1791(2):118-24
3) Metzger MB and Michaelis S  (2009) Analysis of quality control substrates in distinct cellular compartments reveals a unique role for Rpn4p in tolerating misfolded membrane proteins. Mol Biol Cell 20(3):1006-19
4) Tkach JM, et al.  (2012) Dissecting DNA damage response pathways by analysing protein localization and abundance changes during DNA replication stress. Nat Cell Biol 14(9):966-76