TSR3/YOR006C Summary

TSR3 BASIC INFORMATION

Standard Name	TSR3 1
Systematic Name	YOR006C
Feature Type	ORF, Verified
Description	Protein required for correct processing of the 20S pre-rRNA at site D to generate mature 18S rRNA; green fluorescent protein (GFP)-fusion protein localizes to both the cytoplasm and the nucleus (1, 2)
Name Description	Twenty S rRNA accumulation 1

GO Annotations	All TSR3 GO evidence and references
Molecular Function
Manually curated	molecular_function unknown (ND)
Biological Process
Manually curated	maturation of SSU-rRNA (IMP)
Cellular Component
High-throughput	cytoplasm (IDA) nucleus (IDA)

Mutant Phenotype	All TSR3 Phenotype details and references
Classical genetics
null	20S rRNA processing intermediate accumulation: increased 20S pre-rRNA accumulation: increased heat sensitivity: increased 40S ribosomal subunit accumulation: decreased
Large-scale survey
null	competitive fitness: decreased fermentative growth: decreased rate resistance to methyl methanesulfonate: decreased viable

Interactions	TSR3 All interactions details and references
	View additional details at BioGRID
	47 total interaction(s) for 46 unique genes/features.
Physical Interactions	Affinity Capture-RNA: 2 Two-hybrid: 1
Genetic Interactions	Negative Genetic: 24 Positive Genetic: 20

Sequence Information

ChrXV:338622 to 337681 | |

Note: this feature is encoded on the Crick strand.

Last Update

Coordinates: 2006-01-05 | Sequence: 1996-07-31

Subfeature details

	Relative Coordinates	Chromosomal Coordinates	Most Recent Updates
	Relative Coordinates	Chromosomal Coordinates	Coordinates	Sequence
CDS	1..942	338622..337681	2006-01-05	1996-07-31

Post-translational Modifications	PhosphoGRID \| PhosphoPep Database

External Links	All Associated Seq \| Entrez Gene \| Entrez RefSeq Protein \| MIPS \| UniProtKB

Primary SGDID	S000005532

TSR3 RESOURCES

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SGD ORF map	GBrowse

Click on histogram for expression summary
Expression Summary

ADDITIONAL INFORMATION for TSR3

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for TSR3]

1)	Li Z, et al. (2009) Rational extension of the ribosome biogenesis pathway using network-guided genetics. PLoS Biol 7(10):e1000213
2)	Huh WK, et al. (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91

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