IMA2/YOL157C Summary Help

Standard Name IMA2 1, 2
Systematic Name YOL157C
Feature Type ORF, Verified
Description Isomaltase (alpha-1,6-glucosidase/alpha-methylglucosidase); preferred specificity for isomaltose, alpha-methylglucoside, and palatinose, but also exhibits alpha-1,2 glucosidase activity on sucrose and kojibiose, and can cleave the 1,3-alpha linkage of nigerose and turanose and the alpha-1,5 linkage of leucrose in vitro; not required for isomaltose utilization, but Ima2p overexpression allows the ima1 null mutant to grow on isomaltose (1, 2, 3, 4)
Name Description IsoMAltase 1, 2
Chromosomal Location
ChrXV:24294 to 22525 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All IMA2 GO evidence and references
  View Computational GO annotations for IMA2
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Regulators 1 genes
Resources
Large-scale survey
overexpression
Resources
2 total interaction(s) for 2 unique genes/features.
Physical Interactions
  • Affinity Capture-RNA: 1

Genetic Interactions
  • Phenotypic Enhancement: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 589
Molecular Weight (Da) 68,624
Isoelectric Point (pI) 5.29
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXV:24294 to 22525 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1770 24294..22525 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000005517
References cited on this page View Complete Literature Guide for IMA2
1) Teste MA, et al.  (2010) Characterization of a New Multigene Family Encoding Isomaltases in the Yeast Saccharomyces cerevisiae, the IMA Family. J Biol Chem 285(35):26815-24
2) Naumoff DG and Naumov GI  (2010) Discovery of a novel family of alpha-glucosidase IMA genes in yeast Saccharomyces cerevisiae. Dokl Biochem Biophys 432():114-6
3) Brown CA, et al.  (2010) Rapid expansion and functional divergence of subtelomeric gene families in yeasts. Curr Biol 20(10):895-903
4) Deng X, et al.  (2014) Similarities and differences in the biochemical and enzymological properties of the four isomaltases from Saccharomyces cerevisiae. FEBS Open Bio 4():200-12