Standard Name	ZEO1
Systematic Name	YOL109W
Feature Type	ORF, Verified
Description	Peripheral membrane protein of the plasma membrane that interacts with Mid2p; regulates the cell integrity pathway mediated by Pkc1p and Slt2p; the authentic protein is detected in a phosphorylated state in highly purified mitochondria (1, 2)
Name Description	ZEOcin resistance

Chromosomal Location	ChrXV:110297 to 110638 | ORF Map | GBrowse

	View Computational GO annotations for ZEO1
Molecular Function
Manually curated	molecular_function unknown (ND)
Biological Process
Manually curated	fungal-type cell wall organization (IGI, IMP) response to stress (IGI, IMP)
Cellular Component
Manually curated	extrinsic to plasma membrane (IDA)
High-throughput	mitochondrial outer membrane (IDA) mitochondrion (IDA) plasma membrane (IDA)

Large-scale survey
null	auxotrophy competitive fitness: increased haploinsufficient metal resistance: increased resistance to cycloheximide: decreased resistance to streptomycin: decreased resistance to paromomycin: decreased telomere length: increased viable
overexpression	vegetative growth: decreased rate
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	40 total interaction(s) for 36 unique genes/features.
Physical Interactions	Affinity Capture-MS: 13 Affinity Capture-RNA: 2 PCA: 1 Two-hybrid: 2
Genetic Interactions	Dosage Growth Defect: 3 Dosage Rescue: 1 Negative Genetic: 12 Positive Genetic: 3 Synthetic Lethality: 1 Synthetic Rescue: 2
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YeastRC | Organelle DB (UMich) | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP | YeastRC
Homologs	Ashbya (AGD) | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrXV:110297 to 110638 | ORF Map | GBrowse
Last Update	Coordinates: 2006-01-05 | Sequence: 1996-07-31
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..342 110297..110638 2006-01-05 1996-07-31
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI1631 S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain CLIB215 S.c. Strain CLIB324 S.c. Strain CLIB382 S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FL100 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain M22 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain T73 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000005469