WSC3/YOL105C Summary Help

WSC3 BASIC INFORMATION

Standard Name WSC3
Systematic Name YOL105C
Feature Type ORF, Verified
Description Partially redundant sensor-transducer of the stress-activated PKC1-MPK1 signaling pathway involved in maintenance of cell wall integrity; involved in the response to heat shock and other stressors; regulates 1,3-beta-glucan synthesis (1, 2, 3, 4)
Name Description cell Wall integrity and Stress response Component 1
GO Annotations All WSC3 GO evidence and references
    View Computational GO annotations for WSC3
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Mutant Phenotype All WSC3 Phenotype details and references
Large-scale survey
null
Interactions WSC3 All interactions details and references
26 total interaction(s) for 23 unique genes/features.
Physical Interactions
  • Affinity Capture-RNA: 1
  • PCA: 10
  • Two-hybrid: 1

Genetic Interactions
  • Dosage Rescue: 11
  • Phenotypic Enhancement: 1
  • Synthetic Lethality: 1
  • Synthetic Rescue: 1

Sequence Information
ChrXV:115808 to 114138 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Last Update Coordinates: 2006-01-05 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1671 115808..114138 2006-01-05 1996-07-31
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | UniProtKB
Primary SGDIDS000005465

WSC3 RESOURCES

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SGD ORF mapGBrowse
SGD ORF map
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  • Functional Analysis

Click on histogram for expression summary
Expression Summary histogram

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for WSC3]

1) Verna J, et al.  (1997) A family of genes required for maintenance of cell wall integrity and for the stress response in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A 94(25):13804-9
2) Zu T, et al.  (2001) Mutations in WSC genes for putative stress receptors result in sensitivity to multiple stress conditions and impairment of Rlm1-dependent gene expression in Saccharomyces cerevisiae. Mol Genet Genomics 266(1):142-55
3) Sekiya-Kawasaki M, et al.  (2002) Dissection of upstream regulatory components of the Rho1p effector, 1,3-beta-glucan synthase, in Saccharomyces cerevisiae. Genetics 162(2):663-76
4) Wojda I, et al.  (2003) Response to high osmotic conditions and elevated temperature in Saccharomyces cerevisiae is controlled by intracellular glycerol and involves coordinate activity of MAP kinase pathways. Microbiology 149(Pt 5):1193-204