ITR2/YOL103W Summary Help

Standard Name ITR2 1
Systematic Name YOL103W
Alias HRB612
Feature Type ORF, Verified
Description Myo-inositol transporter; member of the sugar transporter superfamily; expressed constitutively; ITR2 has a paralog, ITR1, that arose from the whole genome duplication (1, 2, 3)
Name Description myo-Inositol TRansporter 1
Chromosomal Location
ChrXV:124001 to 125830 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All ITR2 GO evidence and references
  View Computational GO annotations for ITR2
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 92 genes
Resources
Large-scale survey
null
overexpression
Resources
33 total interaction(s) for 30 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 2
  • Affinity Capture-RNA: 1
  • PCA: 1

Genetic Interactions
  • Dosage Growth Defect: 1
  • Negative Genetic: 20
  • Positive Genetic: 5
  • Synthetic Growth Defect: 2
  • Synthetic Rescue: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 609
Molecular Weight (Da) 66,710
Isoelectric Point (pI) 8.25
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXV:124001 to 125830 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2006-01-05 | Sequence: 2003-09-22
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1830 124001..125830 2006-01-05 2003-09-22
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | TCDB | UniProtKB
Primary SGDIDS000005463
References cited on this page View Complete Literature Guide for ITR2
1) Nikawa J, et al.  (1991) Isolation and characterization of two distinct myo-inositol transporter genes of Saccharomyces cerevisiae. J Biol Chem 266(17):11184-91
2) Nikawa J, et al.  (1993) Differential regulation of two myo-inositol transporter genes of Saccharomyces cerevisiae. Mol Microbiol 10(5):955-61
3) Byrne KP and Wolfe KH  (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61