COQ3/YOL096C Summary Help

Standard Name COQ3
Systematic Name YOL096C
Feature Type ORF, Verified
Description O-methyltransferase; catalyzes two different O-methylation steps in ubiquinone (Coenzyme Q) biosynthesis; component of a mitochondrial ubiquinone-synthesizing complex; phosphoprotein (1, 2, 3)
Name Description COenzyme Q
Chromosomal Location
ChrXV:139045 to 138107 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All COQ3 GO evidence and references
  View Computational GO annotations for COQ3
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 1 genes
Resources
Pathways
Classical genetics
null
Large-scale survey
null
Resources
50 total interaction(s) for 45 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 2
  • Affinity Capture-RNA: 2
  • Affinity Capture-Western: 1
  • Co-fractionation: 3
  • Co-purification: 1

Genetic Interactions
  • Negative Genetic: 22
  • Phenotypic Enhancement: 5
  • Phenotypic Suppression: 3
  • Positive Genetic: 7
  • Synthetic Growth Defect: 3
  • Synthetic Rescue: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 312
Molecular Weight (Da) 36,331
Isoelectric Point (pI) 6.95
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXV:139045 to 138107 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 2006-01-05 | Sequence: 2003-09-22
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..939 139045..138107 2006-01-05 2003-09-22
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000005456
References cited on this page View Complete Literature Guide for COQ3
1) Poon WW, et al.  (1999) Yeast and rat Coq3 and Escherichia coli UbiG polypeptides catalyze both O-methyltransferase steps in coenzyme Q biosynthesis. J Biol Chem 274(31):21665-72
2) Marbois B, et al.  (2005) Coq3 and Coq4 define a polypeptide complex in yeast mitochondria for the biosynthesis of coenzyme Q. J Biol Chem 280(21):20231-8
3) Tauche A, et al.  (2008) Ubiquinone biosynthesis in Saccharomyces cerevisiae: the molecular organization of O-methylase Coq3p depends on Abc1p/Coq8p. FEMS Yeast Res 8(8):1263-75