MET22/YOL064C Summary Help

Standard Name MET22 1
Systematic Name YOL064C
Alias HAL2
Feature Type ORF, Verified
Description Bisphosphate-3'-nucleotidase; involved in salt tolerance and methionine biogenesis; dephosphorylates 3'-phosphoadenosine-5'-phosphate and 3'-phosphoadenosine-5'-phosphosulfate, intermediates of the sulfate assimilation pathway (2)
Name Description METhionine requiring 1
Gene Product Alias 3'(2')5'-bisphosphate nucleotidase 2
Chromosomal Location
ChrXV:207176 to 206103 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All MET22 GO evidence and references
  View Computational GO annotations for MET22
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Regulators 9 genes
Resources
Classical genetics
null
Large-scale survey
null
repressible
Resources
158 total interaction(s) for 140 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 3
  • Affinity Capture-RNA: 1

Genetic Interactions
  • Dosage Rescue: 1
  • Negative Genetic: 85
  • Phenotypic Enhancement: 1
  • Phenotypic Suppression: 5
  • Positive Genetic: 29
  • Synthetic Growth Defect: 15
  • Synthetic Lethality: 4
  • Synthetic Rescue: 14

Resources
Expression Summary
histogram
Resources
Length (a.a.) 357
Molecular Weight (Da) 39,149
Isoelectric Point (pI) 6.14
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXV:207176 to 206103 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 2006-01-05 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1074 207176..206103 2006-01-05 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000005425
References cited on this page View Complete Literature Guide for MET22
1) Masselot M and De Robichon-Szulmajster H  (1975) Methionine biosynthesis in Saccharomyces cerevisiae. I. Genetical analysis of auxotrophic mutants. Mol Gen Genet 139(2):121-32
2) Murguia JR, et al.  (1996) The yeast HAL2 nucleotidase is an in vivo target of salt toxicity. J Biol Chem 271(46):29029-33