RRT8/YOL048C Summary Help

Standard Name RRT8 1
Systematic Name YOL048C
Feature Type ORF, Verified
Description Protein involved in spore wall assembly; shares similarity with Lds1p and Lds2p and a strain mutant for all 3 genes exhibits reduced dityrosine fluorescence relative to the single mutants; identified in a screen for mutants with increased levels of rDNA transcription; green fluorescent protein (GFP)-fusion protein localizes to lipid particles; protein abundance increases in response to DNA replication stress (1, 2, 3, 4, 5)
Name Description Regulator of rDNA Transcription 1
Chromosomal Location
ChrXV:241310 to 240204 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All RRT8 GO evidence and references
  View Computational GO annotations for RRT8
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 80 genes
Resources
Classical genetics
null
Large-scale survey
null
Resources
6 total interaction(s) for 6 unique genes/features.
Physical Interactions
  • Affinity Capture-RNA: 1

Genetic Interactions
  • Dosage Lethality: 1
  • Negative Genetic: 2
  • Positive Genetic: 1
  • Synthetic Growth Defect: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 342
Molecular Weight (Da) 39,600
Isoelectric Point (pI) 10.66
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXV:241310 to 240204 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 2003-09-27
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..285 241310..241026 2011-02-03 2003-09-27
Intron 286..363 241025..240948 2011-02-03 2003-09-27
CDS 364..1107 240947..240204 2011-02-03 2003-09-27
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000005408
References cited on this page View Complete Literature Guide for RRT8
1) Hontz RD, et al.  (2009) Genetic Identification of Factors That Modulate Ribosomal DNA Transcription in Saccharomyces cerevisiae. Genetics 182(1):105-19
2) Huh WK, et al.  (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91
3) SGD  (2006) No information available
4) Tkach JM, et al.  (2012) Dissecting DNA damage response pathways by analysing protein localization and abundance changes during DNA replication stress. Nat Cell Biol 14(9):966-76
5) Lin CP, et al.  (2013) A Highly Redundant Gene Network Controls Assembly of the Outer Spore Wall in S. cerevisiae. PLoS Genet 9(8):e1003700