NOG2/YNR053C Summary Help

Standard Name NOG2 1
Systematic Name YNR053C
Alias NUG2 2
Feature Type ORF, Verified
Description Putative GTPase; associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation (1)
Name Description NucleOlar G-protein 1
Chromosomal Location
ChrXIV:723112 to 721120 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All NOG2 GO evidence and references
  View Computational GO annotations for NOG2
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 20 genes
Resources
Classical genetics
null
Large-scale survey
null
reduction of function
Resources
180 total interaction(s) for 78 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 139
  • Affinity Capture-RNA: 3
  • Affinity Capture-Western: 21
  • Co-purification: 3
  • Two-hybrid: 10

Genetic Interactions
  • Dosage Rescue: 1
  • Negative Genetic: 1
  • Positive Genetic: 1
  • Synthetic Lethality: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 486
Molecular Weight (Da) 55,488
Isoelectric Point (pI) 10.29
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXIV:723112 to 721120 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
This feature contains embedded feature(s): SNR191
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 2011-02-03
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..810 723112..722303 2011-02-03 1997-01-28
Intron 811..1342 722302..721771 2011-02-03 2011-02-03
CDS 1343..1993 721770..721120 2011-02-03 1997-01-28
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000005336
References cited on this page View Complete Literature Guide for NOG2
1) Saveanu C, et al.  (2001) Nog2p, a putative GTPase associated with pre-60S subunits and required for late 60S maturation steps. EMBO J 20(22):6475-84
2) Bassler J, et al.  (2001) Identification of a 60S preribosomal particle that is closely linked to nuclear export. Mol Cell 8(3):517-29