YNR048W Summary Help

YNR048W BASIC INFORMATION

Systematic Name YNR048W
Alias CRF1 1
Feature Type ORF, Verified
Description Protein that interacts specifically in vivo with phospholipid translocase (flippase) Dnf3p; similar to Cdc50p, which is an essential interaction partner of the flippase Drs2p (2, 3, 4)
GO Annotations All YNR048W GO evidence and references
    View Computational GO annotations for YNR048W
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Mutant Phenotype All YNR048W Phenotype details and references
Large-scale survey
null
overexpression
Interactions YNR048W All interactions details and references
14 total interaction(s) for 13 unique genes/features.
Physical Interactions
  • Two-hybrid: 2
Genetic Interactions
  • Dosage Rescue: 1
  • Phenotypic Enhancement: 6
  • Phenotypic Suppression: 4
  • Synthetic Growth Defect: 1
Sequence Information
ChrXIV:711633 to 712814 | ORF Map | GBrowse
Gbrowse
Last Update Coordinates: 2010-01-05 | Sequence: 1997-01-28
Subfeature details
Relative
Coordinates		 Chromosomal
Coordinates		 Most Recent Updates
Coordinates Sequence
CDS 1..1182 711633..712814 2010-01-05 1997-01-28
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | UniProtKB
Primary SGDIDS000005331

YNR048W RESOURCES

Click on map for expanded view
SGD ORF mapGBrowse
SGD ORF map
 GBrowse
  • Literature
  • Retrieve Sequences
  • Sequence Analysis Tools
  • Protein Info & Structure
  • Localization Resources
  • Interactions
  • Phenotype Resources
  • Maps & Displays
  • Comparison Resources
  • Functional Analysis

Click on histogram for expression summary
Expression Summary histogram

ADDITIONAL INFORMATION for YNR048W

NOMENCLATURE CONFLICT NOTE

NameRelevanceDescription
CRF1Nomenclature conflictCRF1 has been used to refer to both YDR223W, whose gene product is involved in transcription regulation, and YNR048W, whose gene product is involved in phospholipid translocation.

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for YNR048W]

1) Saito K, et al.  (2004) Cdc50p, a protein required for polarized growth, associates with the Drs2p P-type ATPase implicated in phospholipid translocation in Saccharomyces cerevisiae. Mol Biol Cell 15(7):3418-32
2) Katoh Y and Katoh M  (2004) Identification and characterization of CDC50A, CDC50B and CDC50C genes in silico. Oncol Rep 12(4):939-43
3) Paulusma CC and Oude Elferink RP  (2005) The type 4 subfamily of P-type ATPases, putative aminophospholipid translocases with a role in human disease. Biochim Biophys Acta 1741(1-2):11-24
4) Lenoir G, et al.  (2009) Cdc50p plays a vital role in the ATPase reaction cycle of the putative aminophospholipid transporter drs2p. J Biol Chem 284(27):17956-67