DBP6/YNR038W Summary

DBP6 BASIC INFORMATION

Standard Name	DBP6
Systematic Name	YNR038W
Feature Type	ORF, Verified
Description	Essential protein involved in ribosome biogenesis; putative ATP-dependent RNA helicase of the DEAD-box protein family (1)
Name Description	Dead Box Protein

GO Annotations	All DBP6 GO evidence and references
	View Computational GO annotations for DBP6
Molecular Function
Manually curated	ATP-dependent RNA helicase activity (TAS)
Biological Process
Manually curated	ribosomal large subunit assembly (IMP) rRNA processing (IMP)
Cellular Component
Manually curated	nucleolus (IDA) preribosome, large subunit precursor (IDA)

Mutant Phenotype	All DBP6 Phenotype details and references
Classical genetics
dominant negative	vegetative growth: decreased
Large-scale survey
conditional	heat sensitivity: increased
null	inviable

Interactions	DBP6 All interactions details and references
	22 total interaction(s) for 18 unique genes/features.
Physical Interactions	Affinity Capture-MS: 5 Affinity Capture-RNA: 1 Affinity Capture-Western: 3 Biochemical Activity: 1 PCA: 1
Genetic Interactions	Dosage Rescue: 1 Phenotypic Enhancement: 4 Synthetic Growth Defect: 1 Synthetic Lethality: 5

Sequence Information

ChrXIV:695598 to 697487 | |

Last Update

Coordinates: 2010-01-05 | Sequence: 1997-01-28

Subfeature details

	Relative Coordinates	Chromosomal Coordinates	Most Recent Updates
	Relative Coordinates	Chromosomal Coordinates	Coordinates	Sequence
CDS	1..1890	695598..697487	2010-01-05	1997-01-28

External Links	All Associated Seq \| E.C. \| Entrez Gene \| Entrez RefSeq Protein \| MIPS \| UniProtKB

Primary SGDID	S000005321

DBP6 RESOURCES

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SGD ORF map	GBrowse

Click on histogram for expression summary
Expression Summary

ADDITIONAL INFORMATION for DBP6

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for DBP6]

1)	Kressler D, et al. (1998) Dbp6p is an essential putative ATP-dependent RNA helicase required for 60S-ribosomal-subunit assembly in Saccharomyces cerevisiae. Mol Cell Biol 18(4):1855-65

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