NRM1/YNR009W Summary Help

Standard Name NRM1 1
Systematic Name YNR009W
Feature Type ORF, Verified
Description Transcriptional co-repressor of MBF-regulated gene expression; Nrm1p associates stably with promoters via MCB binding factor (MBF) to repress transcription upon exit from G1 phase (1)
Name Description Negative Regulator of MBF targets 1
Chromosomal Location
ChrXIV:642690 to 643439 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All NRM1 GO evidence and references
  View Computational GO annotations for NRM1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 7 genes
Resources
Classical genetics
null
Large-scale survey
null
Resources
45 total interaction(s) for 37 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 2
  • Affinity Capture-RNA: 2
  • Affinity Capture-Western: 7
  • Biochemical Activity: 12
  • Protein-RNA: 1

Genetic Interactions
  • Dosage Lethality: 1
  • Negative Genetic: 14
  • Positive Genetic: 3
  • Synthetic Growth Defect: 1
  • Synthetic Rescue: 2

Resources
Expression Summary
histogram
Resources
Length (a.a.) 249
Molecular Weight (Da) 27,564
Isoelectric Point (pI) 10.84
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXIV:642690 to 643439 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1997-01-28
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..750 642690..643439 2011-02-03 1997-01-28
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000005292
References cited on this page View Complete Literature Guide for NRM1
1) de Bruin RA, et al.  (2006) Constraining G1-specific transcription to late G1 phase: the MBF-associated corepressor Nrm1 acts via negative feedback. Mol Cell 23(4):483-96