NRM1/YNR009W Summary

NRM1 BASIC INFORMATION

Standard Name	NRM1 1
Systematic Name	YNR009W
Feature Type	ORF, Verified
Description	Transcriptional co-repressor of MBF (MCB binding factor)-regulated gene expression; Nrm1p associates stably with promoters via MBF to repress transcription upon exit from G1 phase (1)
Name Description	Negative Regulator of MBF targets 1

GO Annotations	All NRM1 GO evidence and references
	View Computational GO annotations for NRM1
Molecular Function
Manually curated	transcription repressor activity (IMP, IPI)
Biological Process
Manually curated	negative regulation of transcription (IMP)
Cellular Component
Manually curated	nucleus (IPI)
High-throughput	cytoplasm (IDA) nucleus (IDA)

Mutant Phenotype	All NRM1 Phenotype details and references
Classical genetics
null	viable
Large-scale survey
null	filamentous growth: decreased invasive growth: absent transposable element transposition: increased viable

Interactions	NRM1 All interactions details and references
	17 total interaction(s) for 16 unique genes/features.
Physical Interactions	Affinity Capture-MS: 2 Affinity Capture-RNA: 1 Affinity Capture-Western: 1 Protein-RNA: 1
Genetic Interactions	Phenotypic Enhancement: 8 Phenotypic Suppression: 1 Synthetic Growth Defect: 1 Synthetic Rescue: 2

Sequence Information

ChrXIV:642693 to 643442 | |

Last Update

Coordinates: 2010-01-05 | Sequence: 1997-01-28

Subfeature details

	Relative Coordinates	Chromosomal Coordinates	Most Recent Updates
	Relative Coordinates	Chromosomal Coordinates	Coordinates	Sequence
CDS	1..750	642693..643442	2010-01-05	1997-01-28

External Links	All Associated Seq \| Entrez Gene \| Entrez RefSeq Protein \| MIPS \| UniProtKB

Primary SGDID	S000005292

NRM1 RESOURCES

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SGD ORF map	GBrowse

Click on histogram for expression summary
Expression Summary

ADDITIONAL INFORMATION for NRM1

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for NRM1]

1)	de Bruin RA, et al. (2006) Constraining G1-specific transcription to late G1 phase: the MBF-associated corepressor Nrm1 acts via negative feedback. Mol Cell 23(4):483-96

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