PFS2/YNL317W Summary Help

PFS2 BASIC INFORMATION

Standard Name PFS2
Systematic Name YNL317W
Feature Type ORF, Verified
Description Integral subunit of the pre-mRNA cleavage and polyadenylation factor (CPF) complex; plays an essential role in mRNA 3'-end formation by bridging different processing factors and thereby promoting the assembly of the processing complex (1, 2)
Name Description Polyadenylation Factor Subunit 3
GO Annotations All PFS2 GO evidence and references
    View Computational GO annotations for PFS2
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Mutant Phenotype All PFS2 Phenotype details and references
Classical genetics
null
Large-scale survey
null
Interactions PFS2 All interactions details and references
121 total interaction(s) for 30 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 108
  • Affinity Capture-Western: 5
  • Reconstituted Complex: 6
Genetic Interactions
  • Synthetic Growth Defect: 2
Sequence Information
ChrXIV:40618 to 42015 | ORF Map | GBrowse
Gbrowse
Last Update Coordinates: 1996-07-31 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates		 Chromosomal
Coordinates		 Most Recent Updates
Coordinates Sequence
CDS 1..1398 40618..42015 1996-07-31 1996-07-31
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | UniProtKB
Primary SGDIDS000005261

PFS2 RESOURCES

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SGD ORF mapGBrowse
SGD ORF map
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  • Literature
  • Retrieve Sequences
  • Sequence Analysis Tools
  • Protein Info & Structure
  • Localization Resources
  • Interactions
  • Phenotype Resources
  • Maps & Displays
  • Comparison Resources
  • Functional Analysis

Click on histogram for expression summary
Expression Summary histogram

ADDITIONAL INFORMATION for PFS2

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for PFS2]

1) Ohnacker M, et al.  (2000) The WD-repeat protein pfs2p bridges two essential factors within the yeast pre-mRNA 3'-end-processing complex. EMBO J 19(1):37-47
2) Vo LT, et al.  (2001) Mpe1, a zinc knuckle protein, is an essential component of yeast cleavage and polyadenylation factor required for the cleavage and polyadenylation of mRNA. Mol Cell Biol 21(24):8346-56
3) Keller W and Minvielle-Sebastia L  (1997) A comparison of mammalian and yeast pre-mRNA 3'-end processing. Curr Opin Cell Biol 9(3):329-36