| Standard Name | ZIM17 1 |
|---|---|
| Systematic Name | YNL310C |
| Alias | TIM15 2 , HEP1 3 |
| Feature Type | ORF, Verified |
| Description | Heat shock protein with a zinc finger motif; essential for protein import into mitochondria; may act with Pam18p to facilitate recognition and folding of imported proteins by Ssc1p (mtHSP70) in the mitochondrial matrix (1, 3, 4) |
| Name Description | ZInc finger Motif protein of 17 kDa 1 |
| Chromosomal Location | |
|---|---|
| Note: this feature is encoded on the Crick strand. | |
Gene Ontology Annotations All ZIM17 GO evidence and references
| View Computational GO annotations for ZIM17 | |
| Molecular Function | |
| Manually curated | |
| Biological Process | |
| Manually curated | |
| Cellular Component | |
| Manually curated | |
| High-throughput |
| Retired Name | FMP28 |
|---|
Mutant phenotypes All ZIM17 Phenotype evidence and references
| Classical genetics | |
|---|---|
| null | |
| Large-scale survey | |
| conditional | |
| null | |
| reduction of function | |
| repressible | |
| Resources |
interactions All ZIM17 Interaction evidence and references
| 17 total interaction(s) for 9 unique genes/features. | |
| Physical Interactions |
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| Genetic Interactions |
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| Resources |
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Expression Summary
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| Resources |
Protein Information All ZIM17 Protein evidence and references
| Localization | |
|---|---|
| Phosphorylation | PhosphoGRID | PhosphoPep Database |
| Structure | |
| Homologs |
sequence information
| Note: this feature is encoded on the Crick strand. | |||||||||||||
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| Last Update | Coordinates: 2011-02-03 | Sequence: 2006-05-10 | ||||||||||||
| Subfeature details |
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Analyze Sequence
| S288C only | |
|---|---|
| S288C vs. other species | |
| S288C vs. other strains |
Resources
| External Links | All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB |
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| Primary SGDID | S000005254 |
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References cited on this page View Complete Literature Guide for ZIM17
| 1) | Burri L, et al. (2004) Zim17, a novel zinc finger protein essential for protein import into mitochondria. J Biol Chem 279(48):50243-9 |
| 2) | Yamamoto H, et al. (2005) Identification of a novel member of yeast mitochondrial Hsp70-associated motor and chaperone proteins that facilitates protein translocation across the inner membrane. FEBS Lett 579(2):507-11 |
| 3) | Sichting M, et al. (2005) Maintenance of structure and function of mitochondrial Hsp70 chaperones requires the chaperone Hep1. EMBO J 24(5):1046-56 |
| 4) | Sanjuan Szklarz LK, et al. (2005) Inactivation of the mitochondrial heat shock protein zim17 leads to aggregation of matrix hsp70s followed by pleiotropic effects on morphology and protein biogenesis. J Mol Biol 351(1):206-18 |




