TOS6/YNL300W Summary Help

Standard Name TOS6 1
Systematic Name YNL300W
Feature Type ORF, Uncharacterized
Description Glycosylphosphatidylinositol-dependent cell wall protein; expression is periodic and decreases in respone to ergosterol perturbation or upon entry into stationary phase; depletion increases resistance to lactic acid (2, 3, 4, 5)
Chromosomal Location
ChrXIV:65744 to 66052 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All TOS6 GO evidence and references
  View Computational GO annotations for TOS6
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Regulators 11 genes
Resources
Large-scale survey
null
unspecified
Resources
29 total interaction(s) for 24 unique genes/features.
Physical Interactions
  • Affinity Capture-RNA: 4
  • PCA: 2
  • Protein-RNA: 1

Genetic Interactions
  • Negative Genetic: 15
  • Positive Genetic: 7

Resources
Expression Summary
histogram
Resources
Length (a.a.) 102
Molecular Weight (Da) 10,170
Isoelectric Point (pI) 7.52
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXIV:65744 to 66052 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2005-11-07 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..309 65744..66052 2005-11-07 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000005244
References cited on this page View Complete Literature Guide for TOS6
1) Castillon GA, et al.  (2009) Concentration of GPI-anchored proteins upon ER exit in yeast. Traffic 10(2):186-200
2) Bammert GF and Fostel JM  (2000) Genome-wide expression patterns in Saccharomyces cerevisiae: comparison of drug treatments and genetic alterations affecting biosynthesis of ergosterol. Antimicrob Agents Chemother 44(5):1255-65
3) Hamada K, et al.  (1998) Screening for glycosylphosphatidylinositol (GPI)-dependent cell wall proteins in Saccharomyces cerevisiae. Mol Gen Genet 258(1-2):53-9
4) Tu BP, et al.  (2005) Logic of the yeast metabolic cycle: temporal compartmentalization of cellular processes. Science 310(5751):1152-8
5) Kawahata M, et al.  (2006) Yeast genes involved in response to lactic acid and acetic acid: acidic conditions caused by the organic acids in Saccharomyces cerevisiae cultures induce expression of intracellular metal metabolism genes regulated by Aft1p. FEMS Yeast Res 6(6):924-36