SEC21/YNL287W Summary Help

SEC21 BASIC INFORMATION

Standard Name SEC21 1
Systematic Name YNL287W
Feature Type ORF, Verified
Description Gamma subunit of coatomer, a heptameric protein complex that together with Arf1p forms the COPI coat; involved in ER to Golgi transport of selective cargo (2, 3)
Name Description SECretory
GO Annotations All SEC21 GO evidence and references
    View Computational GO annotations for SEC21
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Mutant Phenotype All SEC21 Phenotype details and references
Classical genetics
conditional
repressible
Large-scale survey
null
overexpression
repressible
Interactions SEC21 All interactions details and references
90 total interaction(s) for 57 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 35
  • Affinity Capture-RNA: 1
  • Affinity Capture-Western: 8
  • Co-fractionation: 4
  • PCA: 4
  • Protein-peptide: 1
  • Reconstituted Complex: 4
  • Two-hybrid: 5
Genetic Interactions
  • Dosage Growth Defect: 2
  • Dosage Lethality: 1
  • Dosage Rescue: 10
  • Phenotypic Enhancement: 1
  • Synthetic Growth Defect: 1
  • Synthetic Lethality: 12
  • Synthetic Rescue: 1
Sequence Information
ChrXIV:91994 to 94801 | ORF Map | GBrowse
Gbrowse
Last Update Coordinates: 2005-11-07 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates		 Chromosomal
Coordinates		 Most Recent Updates
Coordinates Sequence
CDS 1..2808 91994..94801 2005-11-07 1996-07-31
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | UniProtKB
Primary SGDIDS000005231

SEC21 RESOURCES

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SGD ORF mapGBrowse
SGD ORF map
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  • Literature
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  • Sequence Analysis Tools
  • Protein Info & Structure
  • Localization Resources
  • Interactions
  • Phenotype Resources
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  • Comparison Resources
  • Functional Analysis

Click on histogram for expression summary
Expression Summary histogram

ADDITIONAL INFORMATION for SEC21

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for SEC21]

1) Novick P, et al.  (1980) Identification of 23 complementation groups required for post-translational events in the yeast secretory pathway. Cell 21(1):205-15
2) Gaynor EC and Emr SD  (1997) COPI-independent anterograde transport: cargo-selective ER to Golgi protein transport in yeast COPI mutants. J Cell Biol 136(4):789-802
3) Spang A, et al.  (2001) The ADP ribosylation factor-nucleotide exchange factors Gea1p and Gea2p have overlapping, but not redundant functions in retrograde transport from the Golgi to the endoplasmic reticulum. Mol Biol Cell 12(4):1035-45