PRM1/YNL279W Summary Help

Standard Name PRM1 1
Systematic Name YNL279W
Feature Type ORF, Verified
Description Pheromone-regulated multispanning membrane protein; involved in membrane fusion during mating; predicted to have 5 transmembrane segments and a coiled coil domain; localizes to the shmoo tip; regulated by Ste12p (1, 2)
Name Description Pheromone-Regulated Membrane protein 1
Chromosomal Location
ChrXIV:110917 to 112902 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All PRM1 GO evidence and references
  View Computational GO annotations for PRM1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 10 genes
Resources
Classical genetics
null
overexpression
Large-scale survey
null
overexpression
Resources
20 total interaction(s) for 17 unique genes/features.
Physical Interactions
  • Affinity Capture-Western: 2
  • Co-fractionation: 1
  • PCA: 5
  • Two-hybrid: 1

Genetic Interactions
  • Dosage Growth Defect: 1
  • Dosage Lethality: 2
  • Negative Genetic: 1
  • Phenotypic Enhancement: 7

Resources
Expression Summary
histogram
Resources
Length (a.a.) 661
Molecular Weight (Da) 73,352
Isoelectric Point (pI) 6.16
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXIV:110917 to 112902 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2005-11-07 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1986 110917..112902 2005-11-07 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000005223
References cited on this page View Complete Literature Guide for PRM1
1) Heiman MG and Walter P  (2000) Prm1p, a pheromone-regulated multispanning membrane protein, facilitates plasma membrane fusion during yeast mating. J Cell Biol 151(3):719-30
2) White JM and Rose MD  (2001) Yeast mating: getting close to membrane merger. Curr Biol 11(1):R16-20