BNI1/YNL271C Summary Help

BNI1 BASIC INFORMATION

Standard Name BNI1
Systematic Name YNL271C
Alias PPF3 1 , SHE5 2
Feature Type ORF, Verified
Description Formin, nucleates the formation of linear actin filaments, involved in cell processes such as budding and mitotic spindle orientation which require the formation of polarized actin cables, functionally redundant with BNR1 (3, 4, 5, 6, 7)
Name Description Bud Neck Involved 8
GO Annotations All BNI1 GO evidence and references
    View Computational GO annotations for BNI1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Mutant Phenotype All BNI1 Phenotype details and references
Classical genetics
null
unspecified
Large-scale survey
null
Interactions BNI1 All interactions details and references
292 total interaction(s) for 160 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 9
  • Affinity Capture-RNA: 1
  • Affinity Capture-Western: 2
  • Biochemical Activity: 4
  • Co-crystal Structure: 1
  • Reconstituted Complex: 6
  • Two-hybrid: 26
Genetic Interactions
  • Dosage Lethality: 6
  • Dosage Rescue: 10
  • Phenotypic Enhancement: 14
  • Phenotypic Suppression: 5
  • Synthetic Growth Defect: 23
  • Synthetic Lethality: 183
  • Synthetic Rescue: 2
Sequence Information
ChrXIV:135384 to 129523 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Last Update Coordinates: 2005-11-07 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates		 Chromosomal
Coordinates		 Most Recent Updates
Coordinates Sequence
CDS 1..5862 135384..129523 2005-11-07 1996-07-31
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | UniProtKB
Primary SGDIDS000005215

BNI1 RESOURCES

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SGD ORF mapGBrowse
SGD ORF map
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  • Literature
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  • Protein Info & Structure
  • Localization Resources
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  • Functional Analysis

Click on histogram for expression summary
Expression Summary histogram

ADDITIONAL INFORMATION for BNI1

NOMENCLATURE CONFLICT NOTE

NameRelevanceDescription
NSR1Nomenclature conflictBoth BNI1/YNL271C and NSR1/YGR159C have been referred to as SHE5.

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for BNI1]

1) Yorihuzi T and Ohsumi Y  (1994) Saccharomyces cerevisiae MATa mutant cells defective in pointed projection formation in response to alpha-factor at high concentrations. Yeast 10(5):579-94
2) Jansen RP, et al.  (1996) Mother cell-specific HO expression in budding yeast depends on the unconventional myosin myo4p and other cytoplasmic proteins. Cell 84(5):687-97
3) Chang F and Peter M  (2002) Cell biology. Formins set the record straight. Science 297(5581):531-2
4) Pruyne D, et al.  (2002) Role of formins in actin assembly: nucleation and barbed-end association. Science 297(5581):612-5
5) Sagot I, et al.  (2002) An actin nucleation mechanism mediated by Bni1 and profilin. Nat Cell Biol 4(8):626-31
6) Lew DJ  (2002) Formin' actin filament bundles. Nat Cell Biol 4(2):E29-30
7) Dong Y, et al.  (2003) Formin-dependent actin assembly is regulated by distinct modes of Rho signaling in yeast. J Cell Biol 161(6):1081-92
8) Zahner JE, et al.  (1996) Genetic analysis of the bipolar pattern of bud site selection in the yeast Saccharomyces cerevisiae. Mol Cell Biol 16(4):1857-70