| Standard Name | YIF1 |
|---|---|
| Systematic Name | YNL263C |
| Feature Type | ORF, Verified |
| Description | Integral membrane protein required for the fusion of ER-derived COPII transport vesicles with the Golgi; interacts with Yip1p and Yos1p; localizes to the Golgi, the ER, and COPII vesicles; homolog of human YIPF3 (1, 2, 3, 4) |
| Name Description | YIP1-Interacting Factor |
| Chromosomal Location | |
|---|---|
| Note: this feature is encoded on the Crick strand. | |
Gene Ontology Annotations All YIF1 GO evidence and references
| View Computational GO annotations for YIF1 | |
| Molecular Function | |
| Manually curated |
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| Biological Process | |
| Manually curated | |
| Cellular Component | |
| Manually curated | |
| High-throughput |
Mutant phenotypes All YIF1 Phenotype evidence and references
| Large-scale survey | |
|---|---|
| null | |
| reduction of function | |
| repressible | |
| Resources |
interactions All YIF1 Interaction evidence and references
| 82 total interaction(s) for 53 unique genes/features. | |
| Physical Interactions |
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| Genetic Interactions |
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| Resources |
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Expression Summary
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| Resources |
Protein Information All YIF1 Protein evidence and references
| Localization | |
|---|---|
| Phosphorylation | PhosphoGRID | PhosphoPep Database |
| Structure | |
| Homologs |
sequence information
| Note: this feature is encoded on the Crick strand. | |||||||||||||
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| Last Update | Coordinates: 2011-02-03 | Sequence: 1996-07-31 | ||||||||||||
| Subfeature details |
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Analyze Sequence
| S288C only | |
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| S288C vs. other species | |
| S288C vs. other strains |
Resources
| External Links | All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB |
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| Primary SGDID | S000005207 |
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References cited on this page View Complete Literature Guide for YIF1
| 1) | Barrowman J, et al. (2003) The Yip1p.Yif1p complex is required for the fusion competence of endoplasmic reticulum-derived vesicles. J Biol Chem 278(22):19878-84 |
| 2) | Matern H, et al. (2000) A novel Golgi membrane protein is part of a GTPase-binding protein complex involved in vesicle targeting. EMBO J 19(17):4485-92 |
| 3) | Heidtman M, et al. (2005) Yos1p is a novel subunit of the Yip1p-Yif1p complex and is required for transport between the endoplasmic reticulum and the Golgi complex. Mol Biol Cell 16(4):1673-83 |
| 4) | Tanimoto K, et al. (2011) Characterization of YIPF3 and YIPF4, cis-Golgi Localizing Yip domain family proteins. Cell Struct Funct 36(2):171-85 |




