Standard Name	SIP3 1, 2
Systematic Name	YNL257C
Feature Type	ORF, Verified
Description	Transcription cofactor; acts through interaction with DNA-bound Snf1p; C-terminal region has a putative leucine zipper motif; potential Cdc28p substrate; SIP3 has a paralog, YSP1, that arose from the whole genome duplication (2, 3, 4)
Name Description	SNF1-Interacting Protein 1

Chromosomal Location	ChrXIV:164320 to 160631 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.

	View Computational GO annotations for SIP3
Molecular Function
Manually curated	transcription cofactor activity (IDA)
Biological Process
Manually curated	positive regulation of transcription from RNA polymerase II promoter (IDA)
Cellular Component
High-throughput	cytoplasm (IDA) integral to membrane (ISM) plasma membrane (IDA)

Regulatory modules	predicted: cellcycle (299)
Resources	YeTFaSCo

Classical genetics
null	resistance to miconazole: increased
Large-scale survey
null	competitive fitness: decreased competitive fitness: increased dessication resistance: decreased resistance to edelfosine: decreased resistance to neothyonidioside: decreased resistance to amiodarone: decreased resistance to quinine: increased resistance to cycloheximide: decreased resistance to amitrole: decreased resistance to paromomycin: decreased resistance to neomycin: decreased resistance to curcumin: decreased viable
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	54 total interaction(s) for 53 unique genes/features.
Physical Interactions	Affinity Capture-MS: 4 Biochemical Activity: 1 Two-hybrid: 2
Genetic Interactions	Negative Genetic: 45 Phenotypic Enhancement: 1 Synthetic Growth Defect: 1
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YeastRC | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP | YeastRC
Homologs	Ashbya (AGD) | CGD Homologs | CandidaDB Homologs | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrXIV:164320 to 160631 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.
Last Update	Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..3690 164320..160631 2011-02-03 1996-07-31
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain CLIB215 S.c. Strain CLIB324 S.c. Strain EC1118 S.c. Strain FL100 S.c. Strain FostersB S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain Y10 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000005201