Standard Name	SUI1 1
Systematic Name	YNL244C
Alias	MOF2 2 , RFR1
Feature Type	ORF, Verified
Description	Translation initiation factor eIF1; component of a complex involved in recognition of the initiator codon; modulates translation accuracy at the initiation phase (2, 3, 4, 5)
Name Description	SUppressor of Initiator codon 1

Chromosomal Location	ChrXIV:187496 to 187170 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.
	Genetic position: -171 cM

	View Computational GO annotations for SUI1
Molecular Function
Manually curated	translation initiation factor activity (TAS) translation initiation factor binding (IPI)
Biological Process
Manually curated	translational initiation (TAS)
Cellular Component
Manually curated	multi-eIF complex (IDA)

Classical genetics
conditional	M1 dsRNA accumulation: decreased cellular morphology: abnormal heat sensitivity: increased resistance to paromomycin: decreased
Large-scale survey
conditional	heat sensitivity: increased
null	inviable starvation resistance: decreased
overexpression	vegetative growth: decreased rate
reduction of function	competitive fitness: decreased resistance to tunicamycin: decreased
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	133 total interaction(s) for 60 unique genes/features.
Physical Interactions	Affinity Capture-MS: 44 Affinity Capture-RNA: 2 Affinity Capture-Western: 31 Co-crystal Structure: 1 Co-fractionation: 4 Co-purification: 1 Reconstituted Complex: 16 Two-hybrid: 10
Genetic Interactions	Dosage Growth Defect: 2 Dosage Lethality: 1 Dosage Rescue: 6 Phenotypic Suppression: 3 Synthetic Lethality: 8 Synthetic Rescue: 4
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder | YeastRC Two-Hybrid

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	Organelle DB (UMich) | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP | YeastRC
Homologs	Ashbya (AGD) | AspGD Homologs | CGD Homologs | CandidaDB Homologs | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrXIV:187496 to 187170 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.
	Genetic position: -171 cM
Last Update	Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..327 187496..187170 2011-02-03 1996-07-31
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI1631 S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain CLIB215 S.c. Strain CLIB324 S.c. Strain CLIB382 S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain LalvinQA23 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain Y10 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain YPS163 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000005188