YNL194C Summary Help

Systematic Name YNL194C
Feature Type ORF, Verified
Description Integral membrane protein; required for sporulation and plasma membrane sphingolipid content; similar to SUR7; GFP-fusion protein is induced in response to the DNA-damaging agent MMS; GFP-fusion protein is more abundant at MCCs (membrane compartment occupied by Can1) in the presence of glycerol and oleate; YNL194C has a paralog, FMP45, that arose from the whole genome duplication (1, 2, 3, 4, 5)
Chromosomal Location
ChrXIV:273615 to 272710 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All YNL194C GO evidence and references
  View Computational GO annotations for YNL194C
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 9 genes
Resources
Classical genetics
null
Large-scale survey
null
overexpression
Resources
25 total interaction(s) for 17 unique genes/features.
Physical Interactions
  • Affinity Capture-RNA: 2
  • PCA: 3

Genetic Interactions
  • Dosage Growth Defect: 2
  • Negative Genetic: 8
  • Positive Genetic: 9
  • Synthetic Lethality: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 301
Molecular Weight (Da) 34,081
Isoelectric Point (pI) 10.63
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXIV:273615 to 272710 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..906 273615..272710 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000005138
References cited on this page View Complete Literature Guide for YNL194C
1) Young ME, et al.  (2002) The Sur7p family defines novel cortical domains in Saccharomyces cerevisiae, affects sphingolipid metabolism, and is involved in sporulation. Mol Cell Biol 22(3):927-34
2) Byrne KP and Wolfe KH  (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61
3) Walther TC, et al.  (2006) Eisosomes mark static sites of endocytosis. Nature 439(7079):998-1003
4) Lee MW, et al.  (2007) Global protein expression profiling of budding yeast in response to DNA damage. Yeast 24(3):145-54
5) Jung S, et al.  (2013) Global Analysis of Condition-specific Subcellular Protein Distribution and Abundance. Mol Cell Proteomics 12(5):1421-35