Standard Name	PSD1 1
Systematic Name	YNL169C
Feature Type	ORF, Verified
Description	Phosphatidylserine decarboxylase of the mitochondrial inner membrane; converts phosphatidylserine to phosphatidylethanolamine; partly exposed to the mitochondrial intermembrane space (2, 3, 4)
Name Description	PhosphatidylSerine Decarboxylase 1

Chromosomal Location	ChrXIV:317671 to 316169 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.

	View Computational GO annotations for PSD1
Molecular Function
Manually curated	phosphatidylserine decarboxylase activity (IMP)
Biological Process
Manually curated	phosphatidylcholine biosynthetic process (IDA)
Cellular Component
Manually curated	integral to mitochondrial inner membrane (IDA)
High-throughput	mitochondrion (IDA)

Pathways	phosphatidic acid and phospholipid biosynthesis phospholipid biosynthesis superpathway of phospholipid biosynthesis

Classical genetics
null	phosphatidylethanolamine accumulation: decreased phosphatidylcholine accumulation: decreased phosphatidyl-L-serine accumulation: decreased phosphatidylinositol accumulation: increased mitochondrial morphology: abnormal S-Mgm1 accumulation: decreased resistance to nelfinavir: decreased resistance to choline analog G25: increased
Large-scale survey
null	acid pH resistance: decreased competitive fitness: decreased resistance to formaldehyde: decreased vacuolar morphology: abnormal viable
overexpression	vegetative growth: decreased rate
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	462 total interaction(s) for 345 unique genes/features.
Physical Interactions	Affinity Capture-MS: 2 Affinity Capture-Western: 4 PCA: 1
Genetic Interactions	Dosage Growth Defect: 1 Dosage Rescue: 6 Negative Genetic: 324 Phenotypic Enhancement: 5 Phenotypic Suppression: 2 Positive Genetic: 60 Synthetic Growth Defect: 34 Synthetic Haploinsufficiency: 1 Synthetic Lethality: 22
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YeastRC | Organelle DB (UMich) | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP | YeastRC
Homologs	Ashbya (AGD) | AspGD Homologs | CGD Homologs | CandidaDB Homologs | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrXIV:317671 to 316169 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.
Last Update	Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..1503 317671..316169 2011-02-03 1996-07-31
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CEN.PK113-7D S.c. Strain CLIB215 S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FL100 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain LalvinQA23 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain T73 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain Y10 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000005113