MFA2/YNL145W Summary

MFA2 BASIC INFORMATION

Standard Name	MFA2 1
Systematic Name	YNL145W
Feature Type	ORF, Verified
Description	Mating pheromone a-factor, made by a cells; interacts with alpha cells to induce cell cycle arrest and other responses leading to mating; biogenesis involves C-terminal modification, N-terminal proteolysis, and export; also encoded by MFA1 (2, 3)
Name Description	Mating Factor A

GO Annotations	All MFA2 GO evidence and references
	View Computational GO annotations for MFA2
Molecular Function
Manually curated	mating pheromone activity (IMP)
Biological Process
Manually curated	pheromone-dependent signal transduction involved in conjugation with cellular fusion (IGI, IMP)
Cellular Component
Manually curated	extracellular region (IDA)

Mutant Phenotype	All MFA2 Phenotype details and references
Large-scale survey
null	viable

Interactions	MFA2 All interactions details and references
	16 total interaction(s) for 13 unique genes/features.
Physical Interactions	Affinity Capture-RNA: 6 Biochemical Activity: 1 Protein-RNA: 8
Genetic Interactions	Dosage Rescue: 1

Sequence Information

ChrXIV:352416 to 352532 | |

Genetic position: -107.4 cM

Last Update

Coordinates: 2005-11-07 | Sequence: 1996-07-31

Subfeature details

	Relative Coordinates	Chromosomal Coordinates	Most Recent Updates
	Relative Coordinates	Chromosomal Coordinates	Coordinates	Sequence
CDS	1..117	352416..352532	2005-11-07	1996-07-31

External Links	All Associated Seq \| Entrez Gene \| Entrez RefSeq Protein \| MIPS \| UniProtKB

Primary SGDID	S000005089

MFA2 RESOURCES

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SGD ORF map	GBrowse

Click on histogram for expression summary
Expression Summary

ADDITIONAL INFORMATION for MFA2

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for MFA2]

1)	Michaelis, S. (1993) Personal Communication, Mortimer Map Edition 12
2)	Chen P, et al. (1997) Biogenesis of the Saccharomyces cerevisiae mating pheromone a-factor. J Cell Biol 136(2):251-69
3)	Michaelis S and Herskowitz I (1988) The a-factor pheromone of Saccharomyces cerevisiae is essential for mating. Mol Cell Biol 8(3):1309-18

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