MEP2/YNL142W Summary Help

Standard Name MEP2
Systematic Name YNL142W
Feature Type ORF, Verified
Description Ammonium permease involved in regulation of pseudohyphal growth; belongs to a ubiquitous family of cytoplasmic membrane proteins that transport only ammonium (NH4+); expression is under the nitrogen catabolite repression regulation (1, 2)
Chromosomal Location
ChrXIV:357453 to 358952 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All MEP2 GO evidence and references
  View Computational GO annotations for MEP2
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 7 genes
Resources
Classical genetics
null
Large-scale survey
null
overexpression
Resources
61 total interaction(s) for 46 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 1
  • Affinity Capture-RNA: 1
  • Affinity Capture-Western: 7
  • PCA: 1
  • Two-hybrid: 9

Genetic Interactions
  • Dosage Rescue: 19
  • Negative Genetic: 7
  • Phenotypic Enhancement: 1
  • Phenotypic Suppression: 4
  • Positive Genetic: 5
  • Synthetic Growth Defect: 2
  • Synthetic Lethality: 4

Resources
Expression Summary
histogram
Resources
Length (a.a.) 499
Molecular Weight (Da) 53,400
Isoelectric Point (pI) 6.64
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXIV:357453 to 358952 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1500 357453..358952 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | TCDB | UniProtKB
Primary SGDIDS000005086
References cited on this page View Complete Literature Guide for MEP2
1) Marini AM, et al.  (1997) A family of ammonium transporters in Saccharomyces cerevisiae. Mol Cell Biol 17(8):4282-93
2) Lorenz MC and Heitman J  (1998) The MEP2 ammonium permease regulates pseudohyphal differentiation in Saccharomyces cerevisiae. EMBO J 17(5):1236-47