NOP15/YNL110C Summary Help

Standard Name NOP15 1
Systematic Name YNL110C
Feature Type ORF, Verified
Description Constituent of 66S pre-ribosomal particles; involved in 60S ribosomal subunit biogenesis; localizes to both nucleolus and cytoplasm (1, 2)
Name Description NucleOlar Protein 1
Chromosomal Location
ChrXIV:418488 to 417826 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All NOP15 GO evidence and references
  View Computational GO annotations for NOP15
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 6 genes
Resources
Classical genetics
null
Large-scale survey
null
overexpression
reduction of function
Resources
359 total interaction(s) for 218 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 280
  • Affinity Capture-RNA: 3
  • Affinity Capture-Western: 3
  • Co-purification: 1
  • PCA: 2
  • Two-hybrid: 7

Genetic Interactions
  • Dosage Rescue: 1
  • Negative Genetic: 7
  • Positive Genetic: 51
  • Synthetic Growth Defect: 3
  • Synthetic Lethality: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 220
Molecular Weight (Da) 25,447
Isoelectric Point (pI) 10.08
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXIV:418488 to 417826 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..663 418488..417826 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000005054
References cited on this page View Complete Literature Guide for NOP15
1) Harnpicharnchai P, et al.  (2001) Composition and functional characterization of yeast 66S ribosome assembly intermediates. Mol Cell 8(3):505-15
2) Horsey EW, et al.  (2004) Role of the yeast Rrp1 protein in the dynamics of pre-ribosome maturation. RNA 10(5):813-27